CA2226718A1 - Transcorneal drug-release system - Google Patents

Transcorneal drug-release system

Info

Publication number
CA2226718A1
CA2226718A1 CA002226718A CA2226718A CA2226718A1 CA 2226718 A1 CA2226718 A1 CA 2226718A1 CA 002226718 A CA002226718 A CA 002226718A CA 2226718 A CA2226718 A CA 2226718A CA 2226718 A1 CA2226718 A1 CA 2226718A1
Authority
CA
Canada
Prior art keywords
micro
active substance
reservoir
blades
pins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002226718A
Other languages
French (fr)
Other versions
CA2226718C (en
Inventor
Joachim Eicher
Bernd Zierenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002606885A priority Critical patent/CA2606885C/en
Publication of CA2226718A1 publication Critical patent/CA2226718A1/en
Application granted granted Critical
Publication of CA2226718C publication Critical patent/CA2226718C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a transcorneal system for the controlled release of an active substance, comprising an active substance reservoir, a device with micro-pins having capillary openings or micro-blades which are at least 10 µm long and are connected to the active substance reservoir via a liquid-conveying connection for actively transporting the active substance from the reservoir through the micro-pins or along the micro-blades, a device for actively releasing the active substance from the reservoir through the micro--pins or along the micro-blades, wherein the device for actively releasing the active substance is an integrated pump with electronic actuating means. The transcorneal system described is for the controlled release of a drug from a reservoir.
CA002226718A 1995-07-14 1996-07-15 Transcorneal drug-release system Expired - Fee Related CA2226718C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002606885A CA2606885C (en) 1995-07-14 1996-07-15 Micro-pin for a drug-release system

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19525607.7 1995-07-14
DE19525607A DE19525607A1 (en) 1995-07-14 1995-07-14 Transcorneal drug delivery system
PCT/EP1996/003090 WO1997003718A1 (en) 1995-07-14 1996-07-15 Transcorneal drug-release system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002606885A Division CA2606885C (en) 1995-07-14 1996-07-15 Micro-pin for a drug-release system

Publications (2)

Publication Number Publication Date
CA2226718A1 true CA2226718A1 (en) 1997-02-06
CA2226718C CA2226718C (en) 2007-12-11

Family

ID=7766771

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002226718A Expired - Fee Related CA2226718C (en) 1995-07-14 1996-07-15 Transcorneal drug-release system

Country Status (34)

Country Link
US (1) US6132755A (en)
EP (1) EP0840634B1 (en)
JP (1) JPH11509123A (en)
KR (1) KR100430703B1 (en)
CN (1) CN1183979C (en)
AR (1) AR004499A1 (en)
AT (1) ATE207769T1 (en)
AU (1) AU722943B2 (en)
BG (1) BG63142B1 (en)
BR (1) BR9609796A (en)
CA (1) CA2226718C (en)
CO (1) CO4700491A1 (en)
CZ (1) CZ290458B6 (en)
DE (2) DE19525607A1 (en)
DK (1) DK0840634T3 (en)
EE (1) EE04006B1 (en)
ES (1) ES2163035T3 (en)
HK (1) HK1010844A1 (en)
HU (1) HU222342B1 (en)
IL (1) IL122907A0 (en)
MX (1) MX9800401A (en)
NO (1) NO316313B1 (en)
NZ (1) NZ313984A (en)
PL (1) PL181658B1 (en)
PT (1) PT840634E (en)
RO (1) RO118738B1 (en)
RU (1) RU2209640C2 (en)
SK (1) SK284358B6 (en)
TR (1) TR199800048T1 (en)
TW (1) TW375528B (en)
UA (1) UA62918C2 (en)
UY (1) UY24277A1 (en)
WO (1) WO1997003718A1 (en)
ZA (1) ZA965931B (en)

Cited By (11)

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WO2016076442A1 (en) 2014-11-14 2016-05-19 L'oreal Micro-needle sheet for reducing wrinkles and method of forming
WO2019230990A1 (en) 2018-05-30 2019-12-05 L'oreal Microneedle sheet
WO2020004428A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020004666A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020017441A1 (en) 2018-07-17 2020-01-23 L'oreal Microneedle sheet
WO2020130157A1 (en) 2018-12-21 2020-06-25 L'oreal Kit and cosmetic process using microneedle sheet
WO2021125067A1 (en) 2019-12-16 2021-06-24 L'oreal Cosmetic process using microneedle sheet
WO2021256214A1 (en) 2020-06-17 2021-12-23 L'oreal Kit and cosmetic process using microneedle sheet
FR3113843A1 (en) 2020-09-07 2022-03-11 L'oreal KIT AND COSMETIC TREATMENT USING MICRO-NEEDLE SHEET
FR3135206A1 (en) 2022-05-05 2023-11-10 L'oreal Cosmetic process using microneedle sheet
FR3139007A1 (en) 2022-08-23 2024-03-01 L'oreal COMPOSITION SUITABLE FOR COSMETIC TREATMENTS OF KERATINOUS SUBSTANCE

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DE19525607A1 (en) 1997-01-16
PT840634E (en) 2002-02-28
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KR100430703B1 (en) 2004-07-22
ES2163035T3 (en) 2002-01-16

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