CA2219307A1 - Apparatus and method for discriminating flow of blood in a cardiovascular system - Google Patents

Apparatus and method for discriminating flow of blood in a cardiovascular system

Info

Publication number
CA2219307A1
CA2219307A1 CA002219307A CA2219307A CA2219307A1 CA 2219307 A1 CA2219307 A1 CA 2219307A1 CA 002219307 A CA002219307 A CA 002219307A CA 2219307 A CA2219307 A CA 2219307A CA 2219307 A1 CA2219307 A1 CA 2219307A1
Authority
CA
Canada
Prior art keywords
blood
shock
potential
stimulating electrodes
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002219307A
Other languages
French (fr)
Other versions
CA2219307C (en
Inventor
Chris A. Bonnerup
Mohammed Z. Munshi
John P. Rosborough
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intermedics Inc
Original Assignee
Chris A. Bonnerup
Mohammed Z. Munshi
Sulzer Intermedics Inc.
John P. Rosborough
Intermedics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chris A. Bonnerup, Mohammed Z. Munshi, Sulzer Intermedics Inc., John P. Rosborough, Intermedics Inc. filed Critical Chris A. Bonnerup
Publication of CA2219307A1 publication Critical patent/CA2219307A1/en
Application granted granted Critical
Publication of CA2219307C publication Critical patent/CA2219307C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/3918Heart defibrillators characterised by shock pathway, e.g. by electrode configuration

Abstract

An implantable cardiac stimulator includes means for delivering a first electrical shock via implantable stimulating electrodes at a time when there is substantially no flow of blood, as determined by conventional fibrillation detection means. At least one of the stimulating electrodes is disposed in a blood flow path of the cardiovascular system. The first shock is preferably of insufficient energy level to cause defibrillation. A potential is measured as a function of time between the blood-contacting electrode and a reference electrode following delivery of the first shock to obtain a first potential equilibration function under no-flow conditions. A second therapeutic electrical shock, preferably of sufficient energy level to effect defibrillation, is delivered via the stimulating electrodes. A second potential equilibration function is measured following delivery of the second shock. The first and second potential equilibration functions are compared, and if the two functions are sufficiently different in morphology, it is determined that blood is flowing.
CA002219307A 1995-06-02 1996-05-31 Apparatus and method for discriminating flow of blood in a cardiovascular system Expired - Fee Related CA2219307C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/458,952 1995-06-02
US08/458,952 US5782879A (en) 1995-06-02 1995-06-02 Apparatus and method for discriminating flow of blood in a cardiovascular system
PCT/US1996/008180 WO1996038201A1 (en) 1995-06-02 1996-05-31 Apparatus and method for discriminating flow of blood in a cardiovascular system

Publications (2)

Publication Number Publication Date
CA2219307A1 true CA2219307A1 (en) 1996-12-05
CA2219307C CA2219307C (en) 2001-07-24

Family

ID=23822768

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002219307A Expired - Fee Related CA2219307C (en) 1995-06-02 1996-05-31 Apparatus and method for discriminating flow of blood in a cardiovascular system

Country Status (5)

Country Link
US (1) US5782879A (en)
EP (1) EP0828532A1 (en)
JP (1) JP2001501487A (en)
CA (1) CA2219307C (en)
WO (1) WO1996038201A1 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6501990B1 (en) 1999-12-23 2002-12-31 Cardiac Pacemakers, Inc. Extendable and retractable lead having a snap-fit terminal connector
US6463334B1 (en) 1998-11-02 2002-10-08 Cardiac Pacemakers, Inc. Extendable and retractable lead
US6263241B1 (en) 1999-04-30 2001-07-17 Intermedics, Inc. Method and apparatus for treatment of cardiac electromechanical dissociation
US6298267B1 (en) 1999-04-30 2001-10-02 Intermedics Inc. Method and apparatus for treatment of cardiac electromechanical dissociation
US6475214B1 (en) 2000-05-01 2002-11-05 Biosense Webster, Inc. Catheter with enhanced ablation electrode
US6671561B1 (en) 2000-05-01 2003-12-30 Biosense Webster, Inc. Catheter with electrode having hydrogel layer
US6493586B1 (en) * 2000-08-30 2002-12-10 Cardiac Pacemakers, Inc. Site reversion in cardiac rhythm management
US6584362B1 (en) 2000-08-30 2003-06-24 Cardiac Pacemakers, Inc. Leads for pacing and/or sensing the heart from within the coronary veins
US6480740B2 (en) * 2000-12-26 2002-11-12 Cardiac Pacemakers, Inc. Safety pacing in multi-site CRM devices
US7386344B2 (en) * 2004-08-11 2008-06-10 Cardiac Pacemakers, Inc. Pacer with combined defibrillator tailored for bradycardia patients
US6751502B2 (en) 2001-03-14 2004-06-15 Cardiac Pacemakers, Inc. Cardiac rhythm management system with defibrillation threshold prediction
US7191000B2 (en) * 2001-07-31 2007-03-13 Cardiac Pacemakers, Inc. Cardiac rhythm management system for edema
US20030130697A1 (en) * 2001-10-23 2003-07-10 Halperin Henry R. System and/or method for refibrillation of the heart for treatment of post-countershock pulseless electrical activity and/or asystole
US7089055B2 (en) * 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
US7226422B2 (en) 2002-10-09 2007-06-05 Cardiac Pacemakers, Inc. Detection of congestion from monitoring patient response to a recumbent position
US7569018B1 (en) 2003-02-18 2009-08-04 Purdue Research Foundation Apparatus and method for noninvasively detecting the quality of cardiac pumping
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
US7387610B2 (en) 2004-08-19 2008-06-17 Cardiac Pacemakers, Inc. Thoracic impedance detection with blood resistivity compensation
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8874204B2 (en) * 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US7603170B2 (en) 2005-04-26 2009-10-13 Cardiac Pacemakers, Inc. Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance
US7907997B2 (en) 2005-05-11 2011-03-15 Cardiac Pacemakers, Inc. Enhancements to the detection of pulmonary edema when using transthoracic impedance
US7340296B2 (en) 2005-05-18 2008-03-04 Cardiac Pacemakers, Inc. Detection of pleural effusion using transthoracic impedance
US20070049915A1 (en) * 2005-08-26 2007-03-01 Dieter Haemmerich Method and Devices for Cardiac Radiofrequency Catheter Ablation
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US20070270688A1 (en) 2006-05-19 2007-11-22 Daniel Gelbart Automatic atherectomy system
US9119633B2 (en) 2006-06-28 2015-09-01 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8920411B2 (en) 2006-06-28 2014-12-30 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US10028783B2 (en) 2006-06-28 2018-07-24 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US11389232B2 (en) 2006-06-28 2022-07-19 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US7837610B2 (en) 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
US9101779B2 (en) * 2006-10-19 2015-08-11 Uab Research Foundation Method and system for reducing cardiac low pressure states
US8709631B1 (en) 2006-12-22 2014-04-29 Pacesetter, Inc. Bioelectric battery for implantable device applications
US8574737B2 (en) * 2007-04-19 2013-11-05 Pacesetter, Inc. Bioelectric battery for implantable device applications
JP5330381B2 (en) 2007-05-18 2013-10-30 インスティチュート フォー モレキュラー メディスン インコーポレイテッド Method for measuring and using redox potential (ORP)
US8709709B2 (en) 2007-05-18 2014-04-29 Luoxis Diagnostics, Inc. Measurement and uses of oxidative status
US20090088827A1 (en) * 2007-10-02 2009-04-02 Cardiac Pacemakers, Inc Lead assembly providing sensing or stimulation of spaced-apart myocardial contact areas
US8906011B2 (en) 2007-11-16 2014-12-09 Kardium Inc. Medical device for use in bodily lumens, for example an atrium
US8489172B2 (en) 2008-01-25 2013-07-16 Kardium Inc. Liposuction system
US8255052B2 (en) * 2008-04-02 2012-08-28 Cardiac Pacemakers, Inc. Temperature based systems and methods for tachycardia discrimination and therapy
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
WO2011041571A2 (en) 2009-10-01 2011-04-07 Kardium Inc. Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
US9486273B2 (en) 2011-01-21 2016-11-08 Kardium Inc. High-density electrode-based medical device system
CA2764494A1 (en) 2011-01-21 2012-07-21 Kardium Inc. Enhanced medical device for use in bodily cavities, for example an atrium
US9452016B2 (en) 2011-01-21 2016-09-27 Kardium Inc. Catheter system
US11259867B2 (en) 2011-01-21 2022-03-01 Kardium Inc. High-density electrode-based medical device system
SG10201403559UA (en) 2011-02-28 2014-10-30 Aytu Bioscience Inc Method and apparatus for measuring oxidation-reduction potential
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
USD777926S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
USD777925S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
AU2013249126B2 (en) 2012-04-19 2015-10-01 Aytu Bioscience, Inc. Multiple layer gel
US10827977B2 (en) 2012-05-21 2020-11-10 Kardium Inc. Systems and methods for activating transducers
US9198592B2 (en) 2012-05-21 2015-12-01 Kardium Inc. Systems and methods for activating transducers
US9693832B2 (en) 2012-05-21 2017-07-04 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
CA2847665A1 (en) 2012-10-23 2014-04-23 Raphael Bar-Or Methods and systems for measuring and using the oxidation-reduction potential of a biological sample
US10722184B2 (en) 2014-11-17 2020-07-28 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
US10368936B2 (en) 2014-11-17 2019-08-06 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
CN108348756B (en) 2015-11-20 2021-10-22 心脏起搏器股份公司 Single channel coronary vein lead for multi-chamber sensing and pacing

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450984A (en) * 1965-10-21 1969-06-17 Avco Corp Method and apparatus for measuring the flow velocity of an electrolytic fluid by electrolysis
US4291699A (en) * 1978-09-21 1981-09-29 Purdue Research Foundation Method of and apparatus for automatically detecting and treating ventricular fibrillation
JPS5927566B2 (en) * 1980-07-02 1984-07-06 日本光電工業株式会社 electromagnetic blood flow meter
US4450527A (en) * 1982-06-29 1984-05-22 Bomed Medical Mfg. Ltd. Noninvasive continuous cardiac output monitor
US4926868A (en) * 1987-04-15 1990-05-22 Larsen Lawrence E Method and apparatus for cardiac hemodynamic monitor
SE458743B (en) * 1987-08-31 1989-05-08 Hans Ragnar Lagergren IMPLANT PACEMAKER SYSTEM INCLUDING AN IMPULSE GENERATOR WITH MEMORY FUNCTION REGULARLY REGISTERING INTRA-CARDIC EQUAL ECG
DE3732640C1 (en) * 1987-09-28 1989-05-18 Alt Eckhard Medical device for determining physiological functional parameters
US4986270A (en) * 1987-10-06 1991-01-22 Leonard Bloom Hemodynamically responsive system for and method of treating a malfunctioning heart
US4967748A (en) * 1987-10-06 1990-11-06 Leonard Bloom O2 level responsive system for and method of treating a malfunctioning heart
US4905696A (en) * 1987-10-07 1990-03-06 Siemens Aktiengesellschaft Method and apparatus for P-synchronously stimulating the heart of a patient
EP0347708A1 (en) * 1988-06-16 1989-12-27 Cardiac Pacemakers, Inc. Hemodynamic tachyarrhythmia detection
US5318595A (en) * 1989-09-25 1994-06-07 Ferek Petric Bozidar Pacing method and system for blood flow velocity measurement and regulation of heart stimulating signals based on blood flow velocity
US5146414A (en) * 1990-04-18 1992-09-08 Interflo Medical, Inc. Method and apparatus for continuously measuring volumetric flow
US5085213A (en) * 1990-06-01 1992-02-04 Leonard Bloom Hemodynamically responsive system for and method of treating a malfunctioning heart
EP0474957A3 (en) * 1990-09-11 1992-06-24 Bozidar Ferek-Petric Ultrasonic doppler synchronized cardiac electrotherapy device
US5188106A (en) * 1991-03-08 1993-02-23 Telectronics Pacing Systems, Inc. Method and apparatus for chronically monitoring the hemodynamic state of a patient using doppler ultrasound
US5271408A (en) * 1991-03-25 1993-12-21 Siemens Elema Ab Hydrodynamic system for blood flow measurement
US5213098A (en) * 1991-07-26 1993-05-25 Medtronic, Inc. Post-extrasystolic potentiation stimulation with physiologic sensor feedback
US5174299A (en) * 1991-08-12 1992-12-29 Cardiac Pacemakers, Inc. Thermocouple-based blood flow sensor
DE69213657T2 (en) * 1991-11-04 1997-01-23 Cardiac Pacemakers Inc Implantable device for monitoring and stimulating the heart for diagnosis and therapy
US5224475A (en) * 1991-11-20 1993-07-06 Medtronic, Inc. Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation
EP0574608B1 (en) * 1992-06-17 1998-08-19 Pacesetter AB Defibrillator/cardioverter
EP0583499B1 (en) * 1992-08-18 1996-03-06 Pacesetter AB Method for detecting cardial ventricular fibrillation and means for detection and treating of cardial ventricular fibrillation
SE9202663D0 (en) * 1992-09-16 1992-09-16 Siemens Elema Ab IMPLANTABLE HEART DEFIBRILLATOR
SE9300282D0 (en) * 1993-01-29 1993-01-29 Siemens Elema Ab PROCEDURE AND DEVICE TO MEET THE FLOW OF AN ELECTROLYTIC HYDRAULIC
DE4310412C1 (en) * 1993-03-31 1994-07-21 Manfred Dr Zehender Device for signal analysis of the electrical potential profile of the heart excitation
US5314430A (en) * 1993-06-24 1994-05-24 Medtronic, Inc. Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use
SE9302358D0 (en) * 1993-07-07 1993-07-07 Siemens-Elema Ab HJAERTSTIMULATOR
US5602342A (en) * 1994-01-06 1997-02-11 Pacesetter Ab Method and device for measuring the flow of an electrolytic fluid
US5409009A (en) * 1994-03-18 1995-04-25 Medtronic, Inc. Methods for measurement of arterial blood flow
US5503157A (en) * 1995-03-17 1996-04-02 Sramek; Bohumir System for detection of electrical bioimpedance signals

Also Published As

Publication number Publication date
CA2219307C (en) 2001-07-24
US5782879A (en) 1998-07-21
WO1996038201A1 (en) 1996-12-05
EP0828532A1 (en) 1998-03-18
JP2001501487A (en) 2001-02-06

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