CA2219307A1 - Apparatus and method for discriminating flow of blood in a cardiovascular system - Google Patents
Apparatus and method for discriminating flow of blood in a cardiovascular systemInfo
- Publication number
- CA2219307A1 CA2219307A1 CA002219307A CA2219307A CA2219307A1 CA 2219307 A1 CA2219307 A1 CA 2219307A1 CA 002219307 A CA002219307 A CA 002219307A CA 2219307 A CA2219307 A CA 2219307A CA 2219307 A1 CA2219307 A1 CA 2219307A1
- Authority
- CA
- Canada
- Prior art keywords
- blood
- shock
- potential
- stimulating electrodes
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3918—Heart defibrillators characterised by shock pathway, e.g. by electrode configuration
Abstract
An implantable cardiac stimulator includes means for delivering a first electrical shock via implantable stimulating electrodes at a time when there is substantially no flow of blood, as determined by conventional fibrillation detection means. At least one of the stimulating electrodes is disposed in a blood flow path of the cardiovascular system. The first shock is preferably of insufficient energy level to cause defibrillation. A potential is measured as a function of time between the blood-contacting electrode and a reference electrode following delivery of the first shock to obtain a first potential equilibration function under no-flow conditions. A second therapeutic electrical shock, preferably of sufficient energy level to effect defibrillation, is delivered via the stimulating electrodes. A second potential equilibration function is measured following delivery of the second shock. The first and second potential equilibration functions are compared, and if the two functions are sufficiently different in morphology, it is determined that blood is flowing.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/458,952 | 1995-06-02 | ||
US08/458,952 US5782879A (en) | 1995-06-02 | 1995-06-02 | Apparatus and method for discriminating flow of blood in a cardiovascular system |
PCT/US1996/008180 WO1996038201A1 (en) | 1995-06-02 | 1996-05-31 | Apparatus and method for discriminating flow of blood in a cardiovascular system |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2219307A1 true CA2219307A1 (en) | 1996-12-05 |
CA2219307C CA2219307C (en) | 2001-07-24 |
Family
ID=23822768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002219307A Expired - Fee Related CA2219307C (en) | 1995-06-02 | 1996-05-31 | Apparatus and method for discriminating flow of blood in a cardiovascular system |
Country Status (5)
Country | Link |
---|---|
US (1) | US5782879A (en) |
EP (1) | EP0828532A1 (en) |
JP (1) | JP2001501487A (en) |
CA (1) | CA2219307C (en) |
WO (1) | WO1996038201A1 (en) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6501990B1 (en) | 1999-12-23 | 2002-12-31 | Cardiac Pacemakers, Inc. | Extendable and retractable lead having a snap-fit terminal connector |
US6463334B1 (en) | 1998-11-02 | 2002-10-08 | Cardiac Pacemakers, Inc. | Extendable and retractable lead |
US6263241B1 (en) | 1999-04-30 | 2001-07-17 | Intermedics, Inc. | Method and apparatus for treatment of cardiac electromechanical dissociation |
US6298267B1 (en) | 1999-04-30 | 2001-10-02 | Intermedics Inc. | Method and apparatus for treatment of cardiac electromechanical dissociation |
US6475214B1 (en) | 2000-05-01 | 2002-11-05 | Biosense Webster, Inc. | Catheter with enhanced ablation electrode |
US6671561B1 (en) | 2000-05-01 | 2003-12-30 | Biosense Webster, Inc. | Catheter with electrode having hydrogel layer |
US6493586B1 (en) * | 2000-08-30 | 2002-12-10 | Cardiac Pacemakers, Inc. | Site reversion in cardiac rhythm management |
US6584362B1 (en) | 2000-08-30 | 2003-06-24 | Cardiac Pacemakers, Inc. | Leads for pacing and/or sensing the heart from within the coronary veins |
US6480740B2 (en) * | 2000-12-26 | 2002-11-12 | Cardiac Pacemakers, Inc. | Safety pacing in multi-site CRM devices |
US7386344B2 (en) * | 2004-08-11 | 2008-06-10 | Cardiac Pacemakers, Inc. | Pacer with combined defibrillator tailored for bradycardia patients |
US6751502B2 (en) | 2001-03-14 | 2004-06-15 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system with defibrillation threshold prediction |
US7191000B2 (en) * | 2001-07-31 | 2007-03-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system for edema |
US20030130697A1 (en) * | 2001-10-23 | 2003-07-10 | Halperin Henry R. | System and/or method for refibrillation of the heart for treatment of post-countershock pulseless electrical activity and/or asystole |
US7089055B2 (en) * | 2002-06-28 | 2006-08-08 | Cardiac Pacemakers, Inc. | Method and apparatus for delivering pre-shock defibrillation therapy |
US7226422B2 (en) | 2002-10-09 | 2007-06-05 | Cardiac Pacemakers, Inc. | Detection of congestion from monitoring patient response to a recumbent position |
US7569018B1 (en) | 2003-02-18 | 2009-08-04 | Purdue Research Foundation | Apparatus and method for noninvasively detecting the quality of cardiac pumping |
US7320675B2 (en) | 2003-08-21 | 2008-01-22 | Cardiac Pacemakers, Inc. | Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure |
US7387610B2 (en) | 2004-08-19 | 2008-06-17 | Cardiac Pacemakers, Inc. | Thoracic impedance detection with blood resistivity compensation |
US7981065B2 (en) | 2004-12-20 | 2011-07-19 | Cardiac Pacemakers, Inc. | Lead electrode incorporating extracellular matrix |
US8874204B2 (en) * | 2004-12-20 | 2014-10-28 | Cardiac Pacemakers, Inc. | Implantable medical devices comprising isolated extracellular matrix |
US7603170B2 (en) | 2005-04-26 | 2009-10-13 | Cardiac Pacemakers, Inc. | Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance |
US7907997B2 (en) | 2005-05-11 | 2011-03-15 | Cardiac Pacemakers, Inc. | Enhancements to the detection of pulmonary edema when using transthoracic impedance |
US7340296B2 (en) | 2005-05-18 | 2008-03-04 | Cardiac Pacemakers, Inc. | Detection of pleural effusion using transthoracic impedance |
US20070049915A1 (en) * | 2005-08-26 | 2007-03-01 | Dieter Haemmerich | Method and Devices for Cardiac Radiofrequency Catheter Ablation |
US7749249B2 (en) | 2006-02-21 | 2010-07-06 | Kardium Inc. | Method and device for closing holes in tissue |
US20070270688A1 (en) | 2006-05-19 | 2007-11-22 | Daniel Gelbart | Automatic atherectomy system |
US9119633B2 (en) | 2006-06-28 | 2015-09-01 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US8920411B2 (en) | 2006-06-28 | 2014-12-30 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US8449605B2 (en) | 2006-06-28 | 2013-05-28 | Kardium Inc. | Method for anchoring a mitral valve |
US10028783B2 (en) | 2006-06-28 | 2018-07-24 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US11389232B2 (en) | 2006-06-28 | 2022-07-19 | Kardium Inc. | Apparatus and method for intra-cardiac mapping and ablation |
US7837610B2 (en) | 2006-08-02 | 2010-11-23 | Kardium Inc. | System for improving diastolic dysfunction |
US9101779B2 (en) * | 2006-10-19 | 2015-08-11 | Uab Research Foundation | Method and system for reducing cardiac low pressure states |
US8709631B1 (en) | 2006-12-22 | 2014-04-29 | Pacesetter, Inc. | Bioelectric battery for implantable device applications |
US8574737B2 (en) * | 2007-04-19 | 2013-11-05 | Pacesetter, Inc. | Bioelectric battery for implantable device applications |
JP5330381B2 (en) | 2007-05-18 | 2013-10-30 | インスティチュート フォー モレキュラー メディスン インコーポレイテッド | Method for measuring and using redox potential (ORP) |
US8709709B2 (en) | 2007-05-18 | 2014-04-29 | Luoxis Diagnostics, Inc. | Measurement and uses of oxidative status |
US20090088827A1 (en) * | 2007-10-02 | 2009-04-02 | Cardiac Pacemakers, Inc | Lead assembly providing sensing or stimulation of spaced-apart myocardial contact areas |
US8906011B2 (en) | 2007-11-16 | 2014-12-09 | Kardium Inc. | Medical device for use in bodily lumens, for example an atrium |
US8489172B2 (en) | 2008-01-25 | 2013-07-16 | Kardium Inc. | Liposuction system |
US8255052B2 (en) * | 2008-04-02 | 2012-08-28 | Cardiac Pacemakers, Inc. | Temperature based systems and methods for tachycardia discrimination and therapy |
US20090287304A1 (en) | 2008-05-13 | 2009-11-19 | Kardium Inc. | Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve |
WO2011041571A2 (en) | 2009-10-01 | 2011-04-07 | Kardium Inc. | Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve |
US8940002B2 (en) | 2010-09-30 | 2015-01-27 | Kardium Inc. | Tissue anchor system |
US9486273B2 (en) | 2011-01-21 | 2016-11-08 | Kardium Inc. | High-density electrode-based medical device system |
CA2764494A1 (en) | 2011-01-21 | 2012-07-21 | Kardium Inc. | Enhanced medical device for use in bodily cavities, for example an atrium |
US9452016B2 (en) | 2011-01-21 | 2016-09-27 | Kardium Inc. | Catheter system |
US11259867B2 (en) | 2011-01-21 | 2022-03-01 | Kardium Inc. | High-density electrode-based medical device system |
SG10201403559UA (en) | 2011-02-28 | 2014-10-30 | Aytu Bioscience Inc | Method and apparatus for measuring oxidation-reduction potential |
US9072511B2 (en) | 2011-03-25 | 2015-07-07 | Kardium Inc. | Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve |
USD777926S1 (en) | 2012-01-20 | 2017-01-31 | Kardium Inc. | Intra-cardiac procedure device |
USD777925S1 (en) | 2012-01-20 | 2017-01-31 | Kardium Inc. | Intra-cardiac procedure device |
AU2013249126B2 (en) | 2012-04-19 | 2015-10-01 | Aytu Bioscience, Inc. | Multiple layer gel |
US10827977B2 (en) | 2012-05-21 | 2020-11-10 | Kardium Inc. | Systems and methods for activating transducers |
US9198592B2 (en) | 2012-05-21 | 2015-12-01 | Kardium Inc. | Systems and methods for activating transducers |
US9693832B2 (en) | 2012-05-21 | 2017-07-04 | Kardium Inc. | Systems and methods for selecting, activating, or selecting and activating transducers |
CA2847665A1 (en) | 2012-10-23 | 2014-04-23 | Raphael Bar-Or | Methods and systems for measuring and using the oxidation-reduction potential of a biological sample |
US10722184B2 (en) | 2014-11-17 | 2020-07-28 | Kardium Inc. | Systems and methods for selecting, activating, or selecting and activating transducers |
US10368936B2 (en) | 2014-11-17 | 2019-08-06 | Kardium Inc. | Systems and methods for selecting, activating, or selecting and activating transducers |
CN108348756B (en) | 2015-11-20 | 2021-10-22 | 心脏起搏器股份公司 | Single channel coronary vein lead for multi-chamber sensing and pacing |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3450984A (en) * | 1965-10-21 | 1969-06-17 | Avco Corp | Method and apparatus for measuring the flow velocity of an electrolytic fluid by electrolysis |
US4291699A (en) * | 1978-09-21 | 1981-09-29 | Purdue Research Foundation | Method of and apparatus for automatically detecting and treating ventricular fibrillation |
JPS5927566B2 (en) * | 1980-07-02 | 1984-07-06 | 日本光電工業株式会社 | electromagnetic blood flow meter |
US4450527A (en) * | 1982-06-29 | 1984-05-22 | Bomed Medical Mfg. Ltd. | Noninvasive continuous cardiac output monitor |
US4926868A (en) * | 1987-04-15 | 1990-05-22 | Larsen Lawrence E | Method and apparatus for cardiac hemodynamic monitor |
SE458743B (en) * | 1987-08-31 | 1989-05-08 | Hans Ragnar Lagergren | IMPLANT PACEMAKER SYSTEM INCLUDING AN IMPULSE GENERATOR WITH MEMORY FUNCTION REGULARLY REGISTERING INTRA-CARDIC EQUAL ECG |
DE3732640C1 (en) * | 1987-09-28 | 1989-05-18 | Alt Eckhard | Medical device for determining physiological functional parameters |
US4986270A (en) * | 1987-10-06 | 1991-01-22 | Leonard Bloom | Hemodynamically responsive system for and method of treating a malfunctioning heart |
US4967748A (en) * | 1987-10-06 | 1990-11-06 | Leonard Bloom | O2 level responsive system for and method of treating a malfunctioning heart |
US4905696A (en) * | 1987-10-07 | 1990-03-06 | Siemens Aktiengesellschaft | Method and apparatus for P-synchronously stimulating the heart of a patient |
EP0347708A1 (en) * | 1988-06-16 | 1989-12-27 | Cardiac Pacemakers, Inc. | Hemodynamic tachyarrhythmia detection |
US5318595A (en) * | 1989-09-25 | 1994-06-07 | Ferek Petric Bozidar | Pacing method and system for blood flow velocity measurement and regulation of heart stimulating signals based on blood flow velocity |
US5146414A (en) * | 1990-04-18 | 1992-09-08 | Interflo Medical, Inc. | Method and apparatus for continuously measuring volumetric flow |
US5085213A (en) * | 1990-06-01 | 1992-02-04 | Leonard Bloom | Hemodynamically responsive system for and method of treating a malfunctioning heart |
EP0474957A3 (en) * | 1990-09-11 | 1992-06-24 | Bozidar Ferek-Petric | Ultrasonic doppler synchronized cardiac electrotherapy device |
US5188106A (en) * | 1991-03-08 | 1993-02-23 | Telectronics Pacing Systems, Inc. | Method and apparatus for chronically monitoring the hemodynamic state of a patient using doppler ultrasound |
US5271408A (en) * | 1991-03-25 | 1993-12-21 | Siemens Elema Ab | Hydrodynamic system for blood flow measurement |
US5213098A (en) * | 1991-07-26 | 1993-05-25 | Medtronic, Inc. | Post-extrasystolic potentiation stimulation with physiologic sensor feedback |
US5174299A (en) * | 1991-08-12 | 1992-12-29 | Cardiac Pacemakers, Inc. | Thermocouple-based blood flow sensor |
DE69213657T2 (en) * | 1991-11-04 | 1997-01-23 | Cardiac Pacemakers Inc | Implantable device for monitoring and stimulating the heart for diagnosis and therapy |
US5224475A (en) * | 1991-11-20 | 1993-07-06 | Medtronic, Inc. | Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation |
EP0574608B1 (en) * | 1992-06-17 | 1998-08-19 | Pacesetter AB | Defibrillator/cardioverter |
EP0583499B1 (en) * | 1992-08-18 | 1996-03-06 | Pacesetter AB | Method for detecting cardial ventricular fibrillation and means for detection and treating of cardial ventricular fibrillation |
SE9202663D0 (en) * | 1992-09-16 | 1992-09-16 | Siemens Elema Ab | IMPLANTABLE HEART DEFIBRILLATOR |
SE9300282D0 (en) * | 1993-01-29 | 1993-01-29 | Siemens Elema Ab | PROCEDURE AND DEVICE TO MEET THE FLOW OF AN ELECTROLYTIC HYDRAULIC |
DE4310412C1 (en) * | 1993-03-31 | 1994-07-21 | Manfred Dr Zehender | Device for signal analysis of the electrical potential profile of the heart excitation |
US5314430A (en) * | 1993-06-24 | 1994-05-24 | Medtronic, Inc. | Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use |
SE9302358D0 (en) * | 1993-07-07 | 1993-07-07 | Siemens-Elema Ab | HJAERTSTIMULATOR |
US5602342A (en) * | 1994-01-06 | 1997-02-11 | Pacesetter Ab | Method and device for measuring the flow of an electrolytic fluid |
US5409009A (en) * | 1994-03-18 | 1995-04-25 | Medtronic, Inc. | Methods for measurement of arterial blood flow |
US5503157A (en) * | 1995-03-17 | 1996-04-02 | Sramek; Bohumir | System for detection of electrical bioimpedance signals |
-
1995
- 1995-06-02 US US08/458,952 patent/US5782879A/en not_active Expired - Lifetime
-
1996
- 1996-05-31 CA CA002219307A patent/CA2219307C/en not_active Expired - Fee Related
- 1996-05-31 JP JP08536705A patent/JP2001501487A/en active Pending
- 1996-05-31 EP EP96916866A patent/EP0828532A1/en not_active Withdrawn
- 1996-05-31 WO PCT/US1996/008180 patent/WO1996038201A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2219307C (en) | 2001-07-24 |
US5782879A (en) | 1998-07-21 |
WO1996038201A1 (en) | 1996-12-05 |
EP0828532A1 (en) | 1998-03-18 |
JP2001501487A (en) | 2001-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |