CA2195186A1 - Systems and methods for estimating platelet counts - Google Patents
Systems and methods for estimating platelet countsInfo
- Publication number
- CA2195186A1 CA2195186A1 CA002195186A CA2195186A CA2195186A1 CA 2195186 A1 CA2195186 A1 CA 2195186A1 CA 002195186 A CA002195186 A CA 002195186A CA 2195186 A CA2195186 A CA 2195186A CA 2195186 A1 CA2195186 A1 CA 2195186A1
- Authority
- CA
- Canada
- Prior art keywords
- spleen
- systems
- methods
- platelets
- plt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
- A61M1/382—Optimisation of blood component yield
- A61M1/385—Optimisation of blood component yield taking into account of the patient characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0415—Plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
Abstract
Systems and methods take into account that the spleen normally holds a number of platelets in reserve out of circulation. During blood procesing, the spleen releases these platelets into the donor's circulatory system, making them available for collection. The systems and methods estimate the number of platelets N SPLEEN held in reserve by the spleen in a human body. The systems and methods derive a splenic mobilization function Spleen, which can be expressed as a function of a precount of platelets Plt PRE. The systems and methods estimate N SPLEEN where: N SPLEEN = Spleen-1 x Plt PRE x DonVol where DonVol is blood volume in the body. The systems and methods can also estimate the total number of platelets N PLT in a human body, taking the Spleen function into account, where: N PLT
= Plt PRE x Spleen x DonVol.
= Plt PRE x Spleen x DonVol.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/480,601 | 1995-06-07 | ||
US08/480,601 US5759413A (en) | 1995-06-07 | 1995-06-07 | Systems and method for estimating platelet counts using a spleen mobilization function |
PCT/US1996/007672 WO1996040310A1 (en) | 1995-06-07 | 1996-05-22 | Systems and methods for estimating platelet counts |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2195186A1 true CA2195186A1 (en) | 1996-12-19 |
CA2195186C CA2195186C (en) | 2009-04-07 |
Family
ID=23908588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002195186A Expired - Lifetime CA2195186C (en) | 1995-06-07 | 1996-05-22 | Systems and methods for estimating platelet counts |
Country Status (9)
Country | Link |
---|---|
US (2) | US5759413A (en) |
EP (1) | EP0777505B1 (en) |
JP (1) | JP3994292B2 (en) |
AU (1) | AU701419B2 (en) |
CA (1) | CA2195186C (en) |
DE (1) | DE69636969T2 (en) |
ES (1) | ES2284171T3 (en) |
NO (1) | NO970540L (en) |
WO (1) | WO1996040310A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5581687A (en) | 1994-11-10 | 1996-12-03 | Baxter International Inc. | Interactive control systems for medical processing devices |
US6730054B2 (en) * | 1999-10-16 | 2004-05-04 | Baxter International Inc. | Blood collection systems and methods that derive estimated effects upon the donor's blood volume and hematocrit |
US7072769B2 (en) * | 2000-03-01 | 2006-07-04 | Gambro, Inc. | Extracorporeal blood processing information management system |
US7430478B2 (en) | 2000-03-01 | 2008-09-30 | Caridian Bct, Inc. | Blood processing information system with blood loss equivalency tracking |
US20040015399A1 (en) * | 2000-10-12 | 2004-01-22 | Maggio Frank S. | Method and system for verifying exposure to message content delivered via outdoor media or in a concentrated format |
US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
US7211037B2 (en) * | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
US20050049539A1 (en) * | 2003-09-03 | 2005-03-03 | O'hara Gerald P. | Control system for driving fluids through an extracorporeal blood circuit |
US20050241545A1 (en) * | 2004-04-28 | 2005-11-03 | Vargo Richard F Jr | Methods of extending the shelf life of and revitalizing lightweight beads for use in cement compositions |
US7476209B2 (en) * | 2004-12-21 | 2009-01-13 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
EP3254713B1 (en) | 2016-06-08 | 2020-01-08 | Fenwal, Inc. | Systems for therapeutic platelet depletion |
Family Cites Families (47)
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US3916892A (en) * | 1974-04-29 | 1975-11-04 | Haemonetics Corp | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
US4501531A (en) * | 1981-12-15 | 1985-02-26 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
US4481827A (en) * | 1981-12-15 | 1984-11-13 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collection rate display system |
US4458539A (en) * | 1981-12-15 | 1984-07-10 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collected volume display system |
US4447191A (en) * | 1981-12-15 | 1984-05-08 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
SE451946B (en) * | 1982-12-10 | 1987-11-09 | Gambro Lundia Ab | DEVICE FOR THE DISPOSAL OF ONE OR MORE FRACTIONS OF WHOLE BLOOD, PLASMA OR SIMILAR BODY WASHES |
US5034135A (en) * | 1982-12-13 | 1991-07-23 | William F. McLaughlin | Blood fractionation system and method |
US4537561A (en) * | 1983-02-24 | 1985-08-27 | Medical Technology, Ltd. | Peristaltic infusion pump and disposable cassette for use therewith |
US4540406A (en) * | 1983-05-02 | 1985-09-10 | Thoratec Laboratories Corporation | Anticoagulant delivery system for use with an auto-transfusion system |
FR2548541B1 (en) * | 1983-07-07 | 1986-09-12 | Rhone Poulenc Sa | PLASMAPHERESE PROCESS AND APPARATUS FOR USE IN PARTICULAR FOR THIS PROCESS |
FR2548907B1 (en) * | 1983-07-13 | 1985-11-08 | Rhone Poulenc Sa | PLASMAPHERESE PROCESS AND APPARATUS FOR USE IN PARTICULAR FOR THIS PROCESS |
EP0188451B1 (en) * | 1984-06-29 | 1991-12-11 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Blood extraction and reinfusion flow control system and method |
US4692138A (en) * | 1984-10-29 | 1987-09-08 | Mcneilab, Inc. | Pump block for interfacing irradiation chamber to photoactivation patient treatment system |
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JPS6340532A (en) * | 1986-04-05 | 1988-02-20 | 日本光電工業株式会社 | Apparatus for monitoring blood component |
DE3632176A1 (en) * | 1986-09-22 | 1988-04-07 | Fresenius Ag | CONTROL OF A SYSTEM FOR SEPARATING THE COMPONENTS OF BLOOD TAKEN FROM A DONOR "IN VIVO" |
US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
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US4769001A (en) * | 1987-02-25 | 1988-09-06 | Baxter International Inc. | Method and apparatus for calibrating plural pump fluid flow system |
DE3720665A1 (en) * | 1987-06-23 | 1989-01-05 | Schael Wilfried | DEVICE FOR HAEMODIALYSIS AND HAEMOFILTRATION |
US4850995A (en) * | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
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US4867738A (en) * | 1987-09-14 | 1989-09-19 | International Technidyne Corporation | Apparatus and methods for utilizing autotransfusion systems and related equipment |
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DE3909967A1 (en) * | 1989-03-25 | 1990-09-27 | Fresenius Ag | HAEMODIALYSIS DEVICE WITH AUTOMATIC ADJUSTMENT OF THE DIALYSIS FLUID FLOW |
US4995268A (en) * | 1989-09-01 | 1991-02-26 | Ash Medical System, Incorporated | Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument |
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-
1995
- 1995-06-07 US US08/480,601 patent/US5759413A/en not_active Expired - Lifetime
-
1996
- 1996-05-22 ES ES96917831T patent/ES2284171T3/en not_active Expired - Lifetime
- 1996-05-22 EP EP96917831A patent/EP0777505B1/en not_active Expired - Lifetime
- 1996-05-22 WO PCT/US1996/007672 patent/WO1996040310A1/en active IP Right Grant
- 1996-05-22 CA CA002195186A patent/CA2195186C/en not_active Expired - Lifetime
- 1996-05-22 AU AU60242/96A patent/AU701419B2/en not_active Expired
- 1996-05-22 DE DE69636969T patent/DE69636969T2/en not_active Expired - Lifetime
- 1996-05-22 JP JP50071597A patent/JP3994292B2/en not_active Expired - Lifetime
-
1997
- 1997-02-06 NO NO970540A patent/NO970540L/en not_active Application Discontinuation
-
1998
- 1998-02-23 US US09/027,638 patent/US6197202B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2284171T3 (en) | 2007-11-01 |
CA2195186C (en) | 2009-04-07 |
DE69636969D1 (en) | 2007-04-26 |
US6197202B1 (en) | 2001-03-06 |
JP3994292B2 (en) | 2007-10-17 |
US5759413A (en) | 1998-06-02 |
WO1996040310A1 (en) | 1996-12-19 |
AU701419B2 (en) | 1999-01-28 |
DE69636969T2 (en) | 2007-12-20 |
EP0777505A4 (en) | 2000-07-26 |
EP0777505B1 (en) | 2007-03-14 |
AU6024296A (en) | 1996-12-30 |
NO970540L (en) | 1997-04-04 |
JPH10506565A (en) | 1998-06-30 |
EP0777505A1 (en) | 1997-06-11 |
NO970540D0 (en) | 1997-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20160524 |