CA2187002A1 - Remotely Controlled Apparatus and System for Tracking and Locating a Source of Photoemissions - Google Patents

Remotely Controlled Apparatus and System for Tracking and Locating a Source of Photoemissions

Info

Publication number
CA2187002A1
CA2187002A1 CA2187002A CA2187002A CA2187002A1 CA 2187002 A1 CA2187002 A1 CA 2187002A1 CA 2187002 A CA2187002 A CA 2187002A CA 2187002 A CA2187002 A CA 2187002A CA 2187002 A1 CA2187002 A1 CA 2187002A1
Authority
CA
Canada
Prior art keywords
probe
radiopharmaceutical
locating
tracking
sentinel node
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2187002A
Other languages
French (fr)
Other versions
CA2187002C (en
Inventor
Marlin O. Thurston
Karl W. Olson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navidea Biopharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2187002A1 publication Critical patent/CA2187002A1/en
Application granted granted Critical
Publication of CA2187002C publication Critical patent/CA2187002C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/161—Applications in the field of nuclear medicine, e.g. in vivo counting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y10S977/86—Scanning probe structure
    • Y10S977/873—Tip holder

Abstract

System and apparatus particularly suited for tracking a radiopharmaceutical present within a lymph duct and locating a sentinel node within which the radiopharmaceutical has concentrated. A smaller, straight, hand-held probe is employed carrying two hand actuable switches. For tracking procedures, the probe is moved in an undulatory manner wherein the location of the radiopharmaceutical containing duct is determined by observing a graphics readout developed preferably employing a circularly accessed data memory. When the region of the sentinel node is approached, a switch on the probe device is actuated by the surgeon to carry out a sequence of squelching operations until a small node locating region is defined. At that point in the procedure, the straight small probe will be pointed at and in adjacency with the radiopharmaceutical containing sentinel node. The probe-mounted switches areconfigured to apply preset current levels upon the probe pre-amplifier power supply.
These levels are detected, identified by a discriminator and emulating signals are generated. A sterilizable remote switch provides a squelch threaded level trim function.
CA002187002A 1995-10-13 1996-10-02 Remotely controlled apparatus and system for tracking and locating a source of photoemissions Expired - Fee Related CA2187002C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/543,032 1995-10-13
US08/543,032 US5857463A (en) 1995-10-13 1995-10-13 Remotely controlled apparatus and system for tracking and locating a source of photoemissions

Publications (2)

Publication Number Publication Date
CA2187002A1 true CA2187002A1 (en) 1997-04-14
CA2187002C CA2187002C (en) 2000-12-19

Family

ID=24166306

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002187002A Expired - Fee Related CA2187002C (en) 1995-10-13 1996-10-02 Remotely controlled apparatus and system for tracking and locating a source of photoemissions

Country Status (9)

Country Link
US (1) US5857463A (en)
EP (1) EP0768544A3 (en)
JP (1) JPH09189770A (en)
AU (1) AU712444B2 (en)
BR (1) BR9605135A (en)
CA (1) CA2187002C (en)
IL (1) IL119348A (en)
MX (1) MX9604825A (en)
TW (1) TW328910B (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996008208A1 (en) * 1994-09-16 1996-03-21 Biopsys Medical, Inc. Methods and devices for defining and marking tissue
IT1278142B1 (en) * 1995-07-13 1997-11-17 Consiglio Nazionale Ricerche SURGICAL PROBE FOR LOCATION OF TUMORS FOR LAPAROSCOPIC OR INTRACAVITARY USE.
US5682888A (en) * 1996-06-13 1997-11-04 Neoprobe Corporation Apparatus and system for detecting and locating photon emissions with remote switch control
US6638234B2 (en) 1998-03-03 2003-10-28 Senorx, Inc. Sentinel node location and biopsy
CH693074A5 (en) * 1998-05-19 2003-02-14 Kk Holding Ag Circuitry for measuring piezoelectric signals.
US6679851B2 (en) * 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
US6204505B1 (en) * 1998-10-06 2001-03-20 Neoprobe Corporation Surgical probe apparatus and system
US6356782B1 (en) * 1998-12-24 2002-03-12 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US9669113B1 (en) 1998-12-24 2017-06-06 Devicor Medical Products, Inc. Device and method for safe location and marking of a biopsy cavity
US6371904B1 (en) * 1998-12-24 2002-04-16 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6331703B1 (en) 1999-03-12 2001-12-18 Ethicon Endo-Surgery, Inc. Guidance method for radiation detection
US6167297A (en) 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
US7373197B2 (en) * 2000-03-03 2008-05-13 Intramedical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
US6602488B1 (en) 2000-03-03 2003-08-05 Intramedical Imaging, Llc Use of radiopharmaceuticals and intraoperative radiation probe for delivery of medicinal treatments
US6510336B1 (en) 2000-03-03 2003-01-21 Intra Medical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
JP2001324569A (en) * 2000-05-12 2001-11-22 Acrorad Co Ltd Nuclear medicine diagnostic probe
WO2005119025A2 (en) * 2004-06-01 2005-12-15 Spectrum Dynamics Llc Radioactive-emission-measurement optimization to specific body structures
US8909325B2 (en) * 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8036731B2 (en) * 2001-01-22 2011-10-11 Spectrum Dynamics Llc Ingestible pill for diagnosing a gastrointestinal tract
US8565860B2 (en) * 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
JP2004512502A (en) 2000-08-21 2004-04-22 ヴイ−ターゲット　テクノロジーズ　リミテッド Radiation radiation detector with position tracking system and its use in medical systems and procedures
US8489176B1 (en) * 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
DE60139705D1 (en) * 2000-11-09 2009-10-08 Sicel Technologies Inc IN-VIVO DETECTION OF BIOMOLECULAR CONCENTRATIONS BY FLUORESCENT MARKERS
IL157007A0 (en) * 2001-01-22 2004-02-08 Target Technologies Ltd V Ingestible device
US6678546B2 (en) 2001-01-30 2004-01-13 Fischer Imaging Corporation Medical instrument guidance using stereo radiolocation
JP4031618B2 (en) * 2001-02-28 2008-01-09 安西メディカル株式会社 Radiation source detector
US7011814B2 (en) * 2001-04-23 2006-03-14 Sicel Technologies, Inc. Systems, methods and devices for in vivo monitoring of a localized response via a radiolabeled analyte in a subject
WO2003010557A1 (en) * 2001-07-26 2003-02-06 Nihon Medi-Physics Co., Ltd. Radiation detector
US6668277B1 (en) * 2001-09-14 2003-12-23 The Regents Of The University Of California Web-based multi-channel analyzer
US7557353B2 (en) * 2001-11-30 2009-07-07 Sicel Technologies, Inc. Single-use external dosimeters for use in radiation therapies
AU2003242302A1 (en) * 2002-05-14 2003-11-11 Hamamatsu Photonics K.K. Radiation detector
JP4153487B2 (en) * 2002-08-21 2008-09-24 浜松ホトニクス株式会社 Radiation detector
US20040116807A1 (en) * 2002-10-17 2004-06-17 Roni Amrami Blood vessels wall imaging catheter
AU2003276658A1 (en) 2002-11-04 2004-06-07 V-Target Technologies Ltd. Apparatus and methods for imaging and attenuation correction
US20040204646A1 (en) * 2002-11-04 2004-10-14 V-Target Technologies Ltd. Intracorporeal-imaging head
WO2004075032A2 (en) * 2003-02-19 2004-09-02 Sicel Technologies Inc. In vivo fluorescence sensors, systems, and related methods operating in conjunction with fluorescent analytes
US9470801B2 (en) * 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
US8586932B2 (en) 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
CN1981210A (en) * 2004-01-13 2007-06-13 光谱动力学有限责任公司 Multi-dimensional image reconstruction
WO2007010534A2 (en) * 2005-07-19 2007-01-25 Spectrum Dynamics Llc Imaging protocols
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
WO2007054935A2 (en) * 2005-11-09 2007-05-18 Spectrum Dynamics Llc Dynamic spect camera
US9040016B2 (en) * 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
ES2319986T3 (en) * 2004-05-10 2009-05-18 Gfe Gesellschaft Fur Forschungs- Und Entwicklungsservice Mbh HIGH ENERGY GAMMA PROBE WITH CAPACITY TO DETECT A POSITION.
EP1750676B1 (en) * 2004-05-20 2014-07-23 Biosensors International Group, Ltd. Ingestible device platform for the colon
EP1766550A2 (en) 2004-06-01 2007-03-28 Spectrum Dynamics LLC Methods of view selection for radioactive emission measurements
US7855727B2 (en) * 2004-09-15 2010-12-21 Gyrus Acmi, Inc. Endoscopy device supporting multiple input devices
US8000773B2 (en) * 2004-11-09 2011-08-16 Spectrum Dynamics Llc Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
EP1827505A4 (en) * 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radioimaging
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
WO2008059489A2 (en) * 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
US7872235B2 (en) 2005-01-13 2011-01-18 Spectrum Dynamics Llc Multi-dimensional image reconstruction and analysis for expert-system diagnosis
WO2007004269A1 (en) * 2005-06-30 2007-01-11 Hamamatsu Photonics K.K. Radiation detector
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US8111886B2 (en) * 2005-07-19 2012-02-07 Spectrum Dynamics Llc Reconstruction stabilizer and active vision
EP1966984A2 (en) 2005-12-28 2008-09-10 Starhome GmbH Optimal voicemail deposit for roaming cellular telephony
US8894974B2 (en) * 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
US9275451B2 (en) * 2006-12-20 2016-03-01 Biosensors International Group, Ltd. Method, a system, and an apparatus for using and processing multidimensional data
US7669883B2 (en) * 2007-03-29 2010-03-02 Newfrey Llc Air bag bracket/fastener
US8521253B2 (en) * 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
US8344331B1 (en) 2009-03-20 2013-01-01 Devicor Medical Products, Inc. K-alpha probe for detection of photon emissions
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
JP5419670B2 (en) * 2009-12-14 2014-02-19 三菱電機株式会社 Radiation measuring apparatus and diagnostic method thereof
CN102103211A (en) * 2009-12-18 2011-06-22 北京瑞迪泰克技术有限公司 Wound radioactivity measuring instrument
US20120113096A1 (en) * 2010-11-08 2012-05-10 Sony Corporation Medical 3d visualization
AU2014284377B2 (en) 2013-07-01 2019-04-11 Cokiya, Inc. Gamma probe with hand-piece control of detection parameters
JP6392132B2 (en) * 2015-01-22 2018-09-19 株式会社 ケーエンジニアリング Detection device and extraction site placement container
EP3691557B1 (en) * 2017-10-02 2023-06-28 Intuitive Surgical Operations, Inc. Radiation finder tool
US11324475B2 (en) 2018-05-25 2022-05-10 Faxitron Bioptics, Llc Handheld surgical devices with tactile operable controls

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782840A (en) * 1984-03-02 1988-11-08 Neoprobe Corporation Method for locating, differentiating, and removing neoplasms
US5070878A (en) * 1988-11-14 1991-12-10 Neoprobe Corporation Detector and localizer for low energy radiation emissions
US4801803A (en) * 1987-03-17 1989-01-31 Neoprobe Corporation Detector and localizer for low energy radiation emissions
US4889991A (en) * 1988-09-23 1989-12-26 Neoprobe Corporation Gamma radiation detector with enhanced signal treatment
US5441050A (en) * 1992-12-18 1995-08-15 Neoprobe Corporation Radiation responsive surgical instrument
US5429133A (en) * 1992-12-18 1995-07-04 Neoprobe Corporation Radiation responsive laparoscopic instrument

Also Published As

Publication number Publication date
JPH09189770A (en) 1997-07-22
EP0768544A3 (en) 1999-04-28
AU6811796A (en) 1997-04-17
BR9605135A (en) 1998-11-17
US5857463A (en) 1999-01-12
EP0768544A2 (en) 1997-04-16
AU712444B2 (en) 1999-11-04
MX9604825A (en) 1997-09-30
IL119348A0 (en) 1997-01-10
TW328910B (en) 1998-04-01
IL119348A (en) 2000-07-16
CA2187002C (en) 2000-12-19

Similar Documents

Publication Publication Date Title
CA2187002A1 (en) Remotely Controlled Apparatus and System for Tracking and Locating a Source of Photoemissions
SE9202823D0 (en) DEVICE AND PROCEDURE FOR CHARGING ELECTRICAL VEHICLES
EP1281816A3 (en) Excavator data acquisition and control system and process
CA2370960A1 (en) Device for the percutaneous obtainment of 3d-coordinates on the surface of a human or animal organ
EP0340995A3 (en) Apparatus and methods for testing optical devices
AU5123279A (en) Ball retrieving + storage device
DE58908645D1 (en) Remote controlled electrical device.
CA2129940A1 (en) Cable-Locating Apparatus and Method
EP1085478A4 (en) Data distributing system and data selling apparatus therefor, data retrieving apparatus, duplicated data detecting system, and data reproducing apparatus
JPS54128313A (en) Magnetic recorder-reproducer capable of automatic setting of proper bias amount
AU3000097A (en) Solid state beta-sensitive surgical probe
JPS55105893A (en) Driving unit of dynamic memory
WO1997015884A3 (en) Apparatus and method for preserving computer held data following power-off
HK1012711A1 (en) Device for optically measuring the angular velocity of an object
JPS57181121A (en) Electron beam exposing device
JPS5385055A (en) Writing unit for article kind discriminating device
JPS5520564A (en) Data collecting device
JPS5452586A (en) Calibration apparatus
SU1741551A1 (en) Azimuth-signal automatic gain control device for short-range navigation system radio receiver
JPS5559310A (en) Measuring device for barrel inner diameter
JPS5525819A (en) Tape lead-out control system
JPS5683526A (en) Device for discriminating gas turbine output
JPS5470751A (en) Slip issuing device
JPS643724A (en) Information processor
JPS5452952A (en) Control memory mimic device

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20021002