CA2173316A1 - Local polymeric gel cellular therapy - Google Patents
Local polymeric gel cellular therapyInfo
- Publication number
- CA2173316A1 CA2173316A1 CA002173316A CA2173316A CA2173316A1 CA 2173316 A1 CA2173316 A1 CA 2173316A1 CA 002173316 A CA002173316 A CA 002173316A CA 2173316 A CA2173316 A CA 2173316A CA 2173316 A1 CA2173316 A1 CA 2173316A1
- Authority
- CA
- Canada
- Prior art keywords
- tissue
- lumen
- vivo
- polymeric materials
- interior
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
A method for providing a synthetic barrier made of biocompatible polymeric materials in vivo which involves application of a material to a tissue or cellular surface such as the interior surface of a blood vessel, tissue lumen or other hollow space, is disclosed herein. The material may also be applied to tissue contacting surfaces of implantable medical devices. The polymeric materials are characterized by a fluent state which allows application to and, preferably adhesion to, tissue lumen surfaces, which can be increased or altered to a second less fluent state in situ; controlled permeability and degradability; and, in the preferred embodiments, incorporation of bioactive materials for release in vivo, either to the tissue lumen surface or to the interior of the lumen, which alter cell-to-cell interactions. It has also been discovered that tenascin is a mediator of smooth muscle cell migration through interaction with specific integrin components of the cells.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US132,745 | 1993-10-06 | ||
US08/132,745 US5575815A (en) | 1988-08-24 | 1993-10-06 | Local polymeric gel therapy |
US238,931 | 1994-05-06 | ||
US08/238,931 US5843156A (en) | 1988-08-24 | 1994-05-06 | Local polymeric gel cellular therapy |
PCT/US1994/011304 WO1995009659A1 (en) | 1993-10-06 | 1994-10-06 | Local polymeric gel cellular therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2173316A1 true CA2173316A1 (en) | 1995-04-13 |
CA2173316C CA2173316C (en) | 2007-07-10 |
Family
ID=26830694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002173316A Expired - Lifetime CA2173316C (en) | 1993-10-06 | 1994-10-06 | Local polymeric gel cellular therapy |
Country Status (8)
Country | Link |
---|---|
US (2) | US5843156A (en) |
EP (2) | EP0723462B1 (en) |
JP (2) | JP4046195B2 (en) |
AT (1) | ATE424223T1 (en) |
AU (1) | AU703003B2 (en) |
CA (1) | CA2173316C (en) |
DE (1) | DE69435193D1 (en) |
WO (1) | WO1995009659A1 (en) |
Families Citing this family (269)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5914345A (en) * | 1994-10-11 | 1999-06-22 | Endoluminal Therapeutics, Inc. | Treatment of tissues to reduce subsequent response to injury |
US6129761A (en) | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
US6528483B2 (en) | 1995-06-07 | 2003-03-04 | André Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
US6736769B2 (en) | 1996-04-17 | 2004-05-18 | Olivier Bertrand | Radioactivity local delivery system |
WO1997038730A2 (en) * | 1996-04-17 | 1997-10-23 | Olivier Bertrand | Radioactivity local delivery system |
GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
EP1616563A3 (en) * | 1996-05-24 | 2006-01-25 | Angiotech Pharmaceuticals, Inc. | Perivascular administration of anti-angiogenic factors for treating or preventing vascular diseases |
US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
US5840046A (en) * | 1996-06-21 | 1998-11-24 | Medtronic, Inc. | Guidewire having hydrophilic coating |
US8353908B2 (en) | 1996-09-20 | 2013-01-15 | Novasys Medical, Inc. | Treatment of tissue in sphincters, sinuses, and orifices |
IT1289728B1 (en) * | 1996-12-10 | 1998-10-16 | Sorin Biomedica Cardio Spa | SYSTEM AND EQUIPMENT DEVICE THAT INCLUDES IT |
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1994
- 1994-05-06 US US08/238,931 patent/US5843156A/en not_active Expired - Lifetime
- 1994-10-06 EP EP94930606A patent/EP0723462B1/en not_active Expired - Lifetime
- 1994-10-06 EP EP07007682A patent/EP1803476A3/en not_active Withdrawn
- 1994-10-06 AT AT94930606T patent/ATE424223T1/en not_active IP Right Cessation
- 1994-10-06 DE DE69435193T patent/DE69435193D1/en not_active Expired - Fee Related
- 1994-10-06 JP JP51100495A patent/JP4046195B2/en not_active Expired - Lifetime
- 1994-10-06 CA CA002173316A patent/CA2173316C/en not_active Expired - Lifetime
- 1994-10-06 WO PCT/US1994/011304 patent/WO1995009659A1/en active Application Filing
- 1994-10-06 AU AU79671/94A patent/AU703003B2/en not_active Expired
-
1997
- 1997-12-03 US US08/984,614 patent/US6290729B1/en not_active Expired - Fee Related
-
2007
- 2007-09-03 JP JP2007228107A patent/JP2007307429A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US6290729B1 (en) | 2001-09-18 |
EP1803476A2 (en) | 2007-07-04 |
JP2007307429A (en) | 2007-11-29 |
ATE424223T1 (en) | 2009-03-15 |
EP0723462B1 (en) | 2009-03-04 |
JP4046195B2 (en) | 2008-02-13 |
DE69435193D1 (en) | 2009-04-16 |
EP1803476A3 (en) | 2008-06-11 |
JPH09506011A (en) | 1997-06-17 |
WO1995009659A1 (en) | 1995-04-13 |
AU703003B2 (en) | 1999-03-11 |
US5843156A (en) | 1998-12-01 |
EP0723462A1 (en) | 1996-07-31 |
CA2173316C (en) | 2007-07-10 |
AU7967194A (en) | 1995-05-01 |
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