CA2167693A1 - Melanoma-inhibiting protein - Google Patents

Melanoma-inhibiting protein

Info

Publication number
CA2167693A1
CA2167693A1 CA002167693A CA2167693A CA2167693A1 CA 2167693 A1 CA2167693 A1 CA 2167693A1 CA 002167693 A CA002167693 A CA 002167693A CA 2167693 A CA2167693 A CA 2167693A CA 2167693 A1 CA2167693 A1 CA 2167693A1
Authority
CA
Canada
Prior art keywords
melanoma
inhibiting protein
protein
inhibiting
isolation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002167693A
Other languages
French (fr)
Other versions
CA2167693C (en
Inventor
Ulrich Bogdahn
Reinhard Buttner
Brigitte Kaluza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bionet Pharma GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2167693A1 publication Critical patent/CA2167693A1/en
Application granted granted Critical
Publication of CA2167693C publication Critical patent/CA2167693C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention concerns a melanoma-inhibiting protein, nucleic acid sequences coding for this protein, process for the isolation of this protein as well as its use for the production of a therapeutic agent.
CA002167693A 1993-07-20 1994-07-19 Melanoma-inhibiting protein Expired - Lifetime CA2167693C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4324247 1993-07-20
DEP4324247.2 1993-07-20
PCT/EP1994/002369 WO1995003328A2 (en) 1993-07-20 1994-07-19 Melanoma-inhibiting protein

Publications (2)

Publication Number Publication Date
CA2167693A1 true CA2167693A1 (en) 1995-02-02
CA2167693C CA2167693C (en) 2007-01-30

Family

ID=6493222

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002167693A Expired - Lifetime CA2167693C (en) 1993-07-20 1994-07-19 Melanoma-inhibiting protein

Country Status (14)

Country Link
US (1) US5770366A (en)
EP (2) EP0947583A3 (en)
JP (1) JP3435163B2 (en)
CN (1) CN1056617C (en)
AT (1) ATE185152T1 (en)
AU (1) AU7531294A (en)
CA (1) CA2167693C (en)
DE (2) DE4425481A1 (en)
DK (1) DK0710248T3 (en)
ES (1) ES2139751T3 (en)
GR (1) GR3032212T3 (en)
IL (2) IL110385A (en)
WO (1) WO1995003328A2 (en)
ZA (1) ZA945278B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19653358A1 (en) * 1996-12-20 1998-06-25 Boehringer Mannheim Gmbh Immunoassay for the detection of MIA
WO1998031800A2 (en) 1997-01-21 1998-07-23 Human Genome Sciences, Inc. Human proteins
USRE39920E1 (en) 1997-05-30 2007-11-13 Xenomics, Inc. Methods for detection of nucleic acid sequences in urine
US6492144B1 (en) * 1997-05-30 2002-12-10 Diagen Corporation Methods for detection of nucleic acid sequences in urine
EP0945507A1 (en) * 1998-03-27 1999-09-29 Boehringer Mannheim Gmbh Tumor specific expression controll region and its use
US20020103360A1 (en) * 1998-09-01 2002-08-01 Yang Pan Novel protein related to melanoma-inhibiting protein and uses thereof
US20030072767A1 (en) * 1998-09-30 2003-04-17 Alexander Gaiger Compositions and methods for WT1 specific immunotherapy
EP1025871A1 (en) * 1999-01-28 2000-08-09 F. Hoffmann-La Roche Ag Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair
US6713293B1 (en) * 1999-02-08 2004-03-30 Friedrich Grummt Encapsulated cells containing an amplified expression vector as a drug delivery device
CA2377791A1 (en) 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Novel polypeptide and dna thereof
AU2001232967A1 (en) * 2000-01-25 2001-08-07 Hyseq, Inc. Methods and materials relating to novel growth regulatory-like polypeptides and polynucleotides
EP1133994A1 (en) * 2000-03-11 2001-09-19 Biognostik Gesellschaft für biomolekulare Diagnostik mbH A method for reversing the immunosuppressive effects of the Melanoma Inhibitory Activity "MIA"
BR0109455A (en) * 2000-03-23 2003-06-03 Akzo Nobel Nv Use of mia and / or its fragments, method for treating mammals suffering from, or susceptible to, an inflammatory disease, peptide, pharmaceutical composition, and, use of peptides.
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
US20100212037A1 (en) * 2002-10-16 2010-08-19 Anja Katrin Bosserhoff Mia-2 protein
JP5274458B2 (en) * 2006-07-28 2013-08-28 ノバルティス アーゲー Use of melanoma inhibitory activity (MIA) protein as an early indicator for therapeutic response in melanoma
DK2195450T4 (en) * 2007-08-22 2016-10-24 Trovagene Inc Methods of using miRNA FOR DETECTION IN VIVO cell death
SG10201908916UA (en) 2010-04-27 2019-11-28 Scil Tech Gmbh Stable MIA/CD-RAP formulations
WO2012028523A2 (en) * 2010-08-30 2012-03-08 F. Hoffmann-La Roche Ag Prokaryotic expression construct
ITRM20110134A1 (en) * 2011-03-22 2012-09-23 Matteo Bordignon INHIBITORS OF MIA (MELANOMA INHIBITORY ACTIVITY) TO IDENTIFY, PREVENT AND TREAT VITILIGINE

Also Published As

Publication number Publication date
IL154248A0 (en) 2003-09-17
EP0947583A2 (en) 1999-10-06
US5770366A (en) 1998-06-23
WO1995003328A3 (en) 1995-03-16
ATE185152T1 (en) 1999-10-15
CA2167693C (en) 2007-01-30
EP0710248A1 (en) 1996-05-08
EP0710248B1 (en) 1999-09-29
IL154248A (en) 2008-08-07
CN1133049A (en) 1996-10-09
WO1995003328A2 (en) 1995-02-02
JP3435163B2 (en) 2003-08-11
AU7531294A (en) 1995-02-20
GR3032212T3 (en) 2000-04-27
IL110385A (en) 2003-12-10
EP0947583A3 (en) 2000-05-03
CN1056617C (en) 2000-09-20
ES2139751T3 (en) 2000-02-16
JPH09500531A (en) 1997-01-21
ZA945278B (en) 1996-01-19
DE59408791D1 (en) 1999-11-04
DK0710248T3 (en) 2000-04-10
DE4425481A1 (en) 1995-03-02
IL110385A0 (en) 1994-10-21

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MKEX Expiry

Effective date: 20140721