CA2150692A1 - Dispensing device - Google Patents

Dispensing device

Info

Publication number
CA2150692A1
CA2150692A1 CA002150692A CA2150692A CA2150692A1 CA 2150692 A1 CA2150692 A1 CA 2150692A1 CA 002150692 A CA002150692 A CA 002150692A CA 2150692 A CA2150692 A CA 2150692A CA 2150692 A1 CA2150692 A1 CA 2150692A1
Authority
CA
Canada
Prior art keywords
dispensing device
comminution
comminuting
pump
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002150692A
Other languages
French (fr)
Other versions
CA2150692C (en
Inventor
Ronald Alan Coffee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventaira Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2150692A1 publication Critical patent/CA2150692A1/en
Application granted granted Critical
Publication of CA2150692C publication Critical patent/CA2150692C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • B05B5/003—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules by mixing two sprays of opposite polarity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/053—Arrangements for supplying power, e.g. charging power
    • B05B5/0531—Power generators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/16—Arrangements for supplying liquids or other fluent material

Abstract

A device for comminuting a liquid, which comprises at least two electrohydrodynamic comminution means (24) arranged so that in use comminution of opposing polarity are formed which are substantially admixed after formation and a pump (22) for use in the dispensing device.
CA002150692A 1992-12-01 1993-11-26 Dispensing device Expired - Fee Related CA2150692C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9225098.4 1992-12-01
GB929225098A GB9225098D0 (en) 1992-12-01 1992-12-01 Charged droplet spray mixer
PCT/GB1993/002443 WO1994012285A2 (en) 1992-12-01 1993-11-26 Dispensing device

Publications (2)

Publication Number Publication Date
CA2150692A1 true CA2150692A1 (en) 1994-06-09
CA2150692C CA2150692C (en) 2006-09-05

Family

ID=10725936

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002150692A Expired - Fee Related CA2150692C (en) 1992-12-01 1993-11-26 Dispensing device

Country Status (19)

Country Link
US (2) US6105877A (en)
EP (1) EP0671980B1 (en)
JP (1) JPH08504126A (en)
KR (1) KR100289783B1 (en)
CN (1) CN1104262C (en)
AT (1) ATE178814T1 (en)
AU (1) AU685411B2 (en)
CA (1) CA2150692C (en)
DE (1) DE69324499T2 (en)
DK (1) DK0671980T3 (en)
ES (1) ES2130393T3 (en)
GB (1) GB9225098D0 (en)
GR (1) GR3030735T3 (en)
HK (1) HK1012301A1 (en)
MX (1) MX9307490A (en)
NZ (2) NZ314209A (en)
TW (1) TW242576B (en)
WO (1) WO1994012285A2 (en)
ZA (1) ZA938895B (en)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9410658D0 (en) * 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5863497A (en) * 1996-03-11 1999-01-26 The Proctor & Gamble Company Electrostatic hand sanitizer
CN1136821C (en) * 1996-03-11 2004-02-04 普罗克特和甘保尔公司 Electrostatic hand sanitizer
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
WO1998003267A1 (en) 1996-07-23 1998-01-29 Electrosols Ltd. A dispensing device and method for forming material
US20080119772A1 (en) 2001-01-11 2008-05-22 Ronald Alan Coffee Dispensing device and method for forming material
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
KR100517035B1 (en) * 1997-10-27 2005-09-26 세키스이가가쿠 고교가부시키가이샤 Apparatus for spraying microparticles and spraying method using the apparatus, and method for manufacturing liquid crystal display
JP3681561B2 (en) * 1997-12-26 2005-08-10 日本碍子株式会社 Method and apparatus for uniformly mixing substances
SE512386C2 (en) * 1998-07-30 2000-03-06 Microdrug Ag Method and apparatus for classifying electrostatically charged powdery material
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
WO2002018441A2 (en) * 2000-09-01 2002-03-07 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US20040116032A1 (en) * 1999-02-25 2004-06-17 Bowlin Gary L. Electroprocessed collagen
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
BR0009993A (en) * 1999-04-23 2002-01-08 Battelle Memorial Institute Directionally controlled electrohydrodynamic aerosol sprayer, electrically neutral aerosol droplet release device, therapeutic aerosol droplet release device, aerosol droplet release process, and aerosol release device
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
WO2001056596A1 (en) 2000-02-04 2001-08-09 Children's Hospital Research Foundation Use of lysosomal acid lipase for treating atherosclerosis and related diseases
AU2001244391B9 (en) * 2000-04-03 2006-10-05 Ventaira Pharmaceuticals, Inc. Devices and formulations
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
AU6162501A (en) * 2000-05-16 2001-11-26 Univ Minnesota High mass throughput particle generation using multiple nozzle spraying
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
AU3664102A (en) * 2000-12-01 2002-06-11 Battelle Memorial Institute Method for stabilizing biomolecules in liquid formulations
US7674429B2 (en) * 2001-01-22 2010-03-09 Johnsondiversey, Inc. Electrostatic disinfectant delivery
US6546927B2 (en) * 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
CA2440763C (en) 2001-03-22 2010-05-25 Battelle Memorial Institute Liquid formations for electrohydrodymanic spraying containing polymer and suspended particles
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
CA2448022C (en) * 2001-05-21 2013-11-12 Injet Digital Aerosols Limited Compositions for protein delivery via the pulmonary route
EP1273346A1 (en) * 2001-07-05 2003-01-08 Seyonic SA Multi-channel fluid dispensing apparatus
ATE500350T1 (en) * 2001-07-17 2011-03-15 Air Liquide METHOD FOR PRODUCING A PASSIVATED SURFACE
US7832550B2 (en) 2001-07-17 2010-11-16 American Air Liquide, Inc. Reactive gases with concentrations of increased stability and processes for manufacturing same
US20030017359A1 (en) * 2001-07-17 2003-01-23 American Air Liquide, Inc. Increased stability low concentration gases, products comprising same, and methods of making same
MXPA04006629A (en) 2002-01-07 2004-11-10 Aerogen Inc Devices and methods for nebulizing fluids for inhalation.
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
ES2603067T3 (en) 2002-01-15 2017-02-23 Novartis Ag Methods and systems for operating an aerosol generator
AU2002234776A1 (en) * 2002-03-01 2003-09-16 Unilever Plc Electrostatic spraying of a cosmetic composition
ES2572770T3 (en) 2002-05-20 2016-06-02 Novartis Ag Apparatus for providing spray for medical treatment and methods
CN1975415B (en) * 2002-05-29 2010-09-22 液体空气乔治洛德方法利用和研究的具有监督和管理委员会的有限公司 Preparation method for article comprising an acid gas and a matrix gas
DE10228280A1 (en) * 2002-06-25 2004-01-29 Institut für Chemo- und Biosensorik Münster e.V. i.Ins. Device for coating three-dimensional surfaces of substrate e.g. for coating semiconductors with a photoresist comprises spray sources each having a capillary provided with an electrode and arranged in a spray head
US20060179491A1 (en) * 2002-11-12 2006-08-10 Brian Graham Process for treating non-human animals
ZA200504940B (en) 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
US7849850B2 (en) * 2003-02-28 2010-12-14 Battelle Memorial Institute Nozzle for handheld pulmonary aerosol delivery device
AU2004220457A1 (en) 2003-03-12 2004-09-23 Celgene Corporation 7-amino- isoindolyl compounds amd their pharmaceutical uses
US20040241750A1 (en) * 2003-03-24 2004-12-02 David Nordman Novel methods for determining the negative control value for multi-analyte assays
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0308021D0 (en) * 2003-04-07 2003-05-14 Aerstream Technology Ltd Spray electrode
MXPA05010747A (en) 2003-04-11 2006-05-25 Ptc Therapeutics Inc 1,2,4-oxadiazole benzoic acid compounds.
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
DE10334591B4 (en) * 2003-07-28 2006-03-30 International Flavors & Fragrances Inc. Method for distributing liquid fragrances and apparatus for carrying out the method
US7230003B2 (en) 2003-09-09 2007-06-12 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
DE10344135A1 (en) * 2003-09-24 2005-05-04 Karlsruhe Forschzent Device for applying electro-spray coatings to electrically non-conducting surfaces has electrospray capillary for introducing, electrically charging electrospray onto surfaces, periodically repeats compensation, dissipation of charges
US20050079113A1 (en) * 2003-10-09 2005-04-14 Selander Raymond K. Fan-driven air freshener
DE10349472B4 (en) * 2003-10-21 2006-01-19 Forschungszentrum Karlsruhe Gmbh Coating device for polymers
WO2005051942A1 (en) 2003-11-19 2005-06-09 Signal Pharmaceuticals, Llc Indazole compounds and methods of use thereof as protein kinase inhibitors
NL1025556C1 (en) * 2004-02-24 2005-08-26 Jacob Korevaar Device and method for administering a fluid to a human or mammal.
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
WO2006017351A1 (en) 2004-07-12 2006-02-16 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
JP2008505979A (en) 2004-07-12 2008-02-28 ゼノポート，インコーポレイティド Propofol amino acid derivative prodrugs, compositions, and methods of use thereof
US20080259519A1 (en) 2004-09-14 2008-10-23 Battelle Memorial Institute Highly-Aqueous, Non-Respirable Aerosols Containing Biologically-Active Ingredients, Method of Making, and Device Therefor
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7360724B2 (en) 2004-10-20 2008-04-22 The Procter & Gamble Company Electrostatic spray nozzle with internal and external electrodes
SI2561872T1 (en) 2004-12-17 2015-02-27 Anadys Pharmaceuticals, Inc. 3, 5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO Š4,5-dĆPYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF
FR2879482B1 (en) * 2004-12-20 2007-03-30 Oreal DEVICE FOR SPRAYING A PRODUCT, IN PARTICULAR A FRAGRANCE
US7619110B2 (en) 2004-12-23 2009-11-17 Xenoport, Inc. Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof
US7798420B2 (en) * 2005-02-11 2010-09-21 Battelle Memorial Institute Aerosol dispensing device and method
WO2006091790A1 (en) 2005-02-23 2006-08-31 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
DE102005016829A1 (en) 2005-04-12 2006-11-02 Iff International Flavors & Fragrances Method, nozzle and device for atomizing active substances contained in a liquid
BRPI0611198B1 (en) 2005-05-25 2018-02-06 Aerogen, Inc. VIBRATION SYSTEMS AND METHODS
EP1928881A2 (en) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs of active agents
US20090297496A1 (en) * 2005-09-08 2009-12-03 Childrens Hospital Medical Center Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases
GB0524979D0 (en) 2005-12-07 2006-01-18 Queen Mary & Westfield College An electrospray device and a method of electrospraying
WO2007081387A1 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices, methods of use, and kits for performing diagnostics
US7951428B2 (en) * 2006-01-31 2011-05-31 Regents Of The University Of Minnesota Electrospray coating of objects
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
EP2529761B1 (en) 2006-01-31 2017-06-14 Nanocopoeia, Inc. Nanoparticle coating of surfaces
WO2007094835A1 (en) 2006-02-14 2007-08-23 Ventaira Pharmaceuticals, Inc. Dissociated discharge ehd sprayer with electric field shield
US7524848B2 (en) 2006-03-23 2009-04-28 Amgen Inc. Diaza heterocyclic amide compounds and their uses
DE102006017002B3 (en) * 2006-04-11 2007-01-11 Pari GmbH Spezialisten für effektive Inhalation Nebulizer for inhalation therapy comprises compressed gas outlet openings arranged in a row to which are assigned fluid outlet openings forming a nozzle with the gas outlet openings
US9074242B2 (en) 2010-02-12 2015-07-07 Raindance Technologies, Inc. Digital analyte analysis
US20080003142A1 (en) 2006-05-11 2008-01-03 Link Darren R Microfluidic devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
DK2046393T3 (en) 2006-05-26 2014-05-12 Signature Therapeutics Inc CONTROLLED RELEASE OF PHENOL OPIOIDS
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
WO2007145834A2 (en) 2006-06-08 2007-12-21 Amgen Inc. Benzamide derivatives and uses related thereto
US7673819B2 (en) * 2006-06-26 2010-03-09 Battelle Memorial Institute Handheld sprayer with removable cartridge and method of using same
JP5306194B2 (en) 2006-06-22 2013-10-02 アナディス ファーマシューティカルズ インク Pyro [1,2-b] pyridazinone compounds
MX2008016518A (en) 2006-06-22 2009-01-19 Anadys Pharmaceuticals Inc PRODRUGS OF 5-AMINO-3-(3'-DEOXY-beta-D-RIBOFURANOSYL)-THIAZOLO[4,5- d] PYRIMIDIN-2,7-DIONE.
WO2008002556A1 (en) * 2006-06-26 2008-01-03 Battelle Memorial Institute Cartridge having self-actuating seal for a wetted lead screw
ATE499940T1 (en) 2006-07-18 2011-03-15 Anadys Pharmaceuticals Inc CARBONATE AND CARBAMAT PRODRUGS OF THIAZOLO Δ4,5-DÜ-PYRIMIDINES
AU2007275301A1 (en) 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1
US9012390B2 (en) 2006-08-07 2015-04-21 Raindance Technologies, Inc. Fluorocarbon emulsion stabilizing surfactants
US9040816B2 (en) * 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
FR2910254B1 (en) * 2006-12-20 2009-04-17 Oreal PIEZOELECTRIC SPRAY SYSTEM AND CORRESPONDING REFILL
FR2910253B1 (en) * 2006-12-20 2010-03-12 Oreal METHOD FOR DISPENSING A PRODUCT SPRAYED BY A PIEZOELECTRIC SPRAY SYSTEM AND A SPRAY SYSTEM FOR IMPLEMENTING SUCH A METHOD
EP2121580A2 (en) 2006-12-26 2009-11-25 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
EP2111305A2 (en) * 2007-01-31 2009-10-28 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US20080269665A1 (en) * 2007-04-24 2008-10-30 Johan Petersen Chemotherapy delivery device
GB0709517D0 (en) 2007-05-17 2007-06-27 Queen Mary & Westfield College An electrostatic spraying device and a method of electrostatic spraying
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
ES2435799T3 (en) 2008-10-09 2013-12-23 Anadys Pharmaceuticals, Inc. A method of inhibiting hepatitis C virus by combining a 5,6-dihydro-1H-pyridin-2-one and one or more additional antiviral compounds
ITRM20090039A1 (en) * 2009-01-29 2010-07-30 Uni Degli Studi Di Roma To R Vergata SOLID MICRO OR NANOPARTICLE DISPERSION SYSTEM IN A LIQUID PHASE
GB0903134D0 (en) * 2009-02-24 2009-04-08 Osmotex Ag Charged particle motion inducing apparatus
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
US20110174304A1 (en) * 2010-01-21 2011-07-21 Triplett Ii Michael D Electrohydrodynamic aerosolization device having a time varying voltage
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
JP5429993B2 (en) * 2010-03-04 2014-02-26 国立大学法人東京工業大学 Odor generator
EP2561333B1 (en) * 2010-04-19 2015-11-25 Battelle Memorial Institute Electrohydrodynamic spraying
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
EP3859011A1 (en) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Methods for forming mixed droplets
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
WO2012167142A2 (en) 2011-06-02 2012-12-06 Raindance Technolgies, Inc. Enzyme quantification
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
JP5892708B2 (en) * 2011-06-16 2016-03-23 国立研究開発法人産業技術総合研究所 Electrospray micro reaction field forming apparatus and chemical reaction control method
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
JP5762872B2 (en) * 2011-07-29 2015-08-12 住友化学株式会社 Electrostatic spraying equipment
US10350409B2 (en) 2013-03-15 2019-07-16 Ottfried Waldenburg Instrument for and method of treating venomous bites
US20150053786A1 (en) * 2013-08-21 2015-02-26 Trimble Navigation Limited Intelligent precision irrigation system
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
CN104138630B (en) * 2014-07-30 2017-05-10 北京银河之舟科技有限公司 Respiratory tract drug delivery device and method
JP6083031B2 (en) * 2015-05-15 2017-02-22 国立研究開発法人産業技術総合研究所 Submerged electrospray method and submerged electrospray apparatus
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US9808452B2 (en) 2015-10-01 2017-11-07 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
US20170095834A1 (en) * 2015-10-05 2017-04-06 William Brian Kinard Electrostatic deposition
US10455863B2 (en) 2016-03-03 2019-10-29 Altria Client Services Llc Cartridge for electronic vaping device
US10433580B2 (en) 2016-03-03 2019-10-08 Altria Client Services Llc Methods to add menthol, botanic materials, and/or non-botanic materials to a cartridge, and/or an electronic vaping device including the cartridge
US10368580B2 (en) 2016-03-08 2019-08-06 Altria Client Services Llc Combined cartridge for electronic vaping device
US10357060B2 (en) 2016-03-11 2019-07-23 Altria Client Services Llc E-vaping device cartridge holder
US10368581B2 (en) 2016-03-11 2019-08-06 Altria Client Services Llc Multiple dispersion generator e-vaping device
EP3595663A4 (en) 2017-03-17 2021-01-13 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
EP3773614A1 (en) 2018-04-12 2021-02-17 Matrx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
CN109037023B (en) * 2018-06-06 2020-03-10 清华大学深圳研究生院 Device and method for generating neutral spray and substance detection equipment
WO2020080347A1 (en) * 2018-10-17 2020-04-23 住友化学株式会社 Electrostatic spraying apparatus
CN110755699A (en) * 2019-09-18 2020-02-07 浙江省北大信息技术高等研究院 Implantable electroosmotic micropump device
CN111388018B (en) * 2020-03-20 2023-09-19 威图姆卡医疗中心 Method and device for collecting lower respiratory tract sample, air disinfection method and device thereof
GB2598964A (en) * 2020-09-22 2022-03-23 Brian King Andrew Methods and apparatus for inducing chemical reactions using electro-statics

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2723646A (en) * 1950-04-01 1955-11-15 Ransburg Electro Coating Corp Apparatus for electrostatic atomization and coating
US2945443A (en) * 1957-08-22 1960-07-19 Gen Electric Pump operation
US3096762A (en) 1962-02-12 1963-07-09 Waterbury Pressed Metal Co Oral breathing device
US3131131A (en) * 1962-04-03 1964-04-28 Socony Mobil Oil Co Inc Electrostatic mixing in microbial conversions
US3232292A (en) 1962-10-12 1966-02-01 Arizona Nucleonics Inc Ionized aerosols
US3456646A (en) 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3565070A (en) 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3837573A (en) 1972-03-02 1974-09-24 W Wagner Apparatus for electrified spraying
US3958959A (en) 1972-11-02 1976-05-25 Trw Inc. Method of removing particles and fluids from a gas stream by charged droplets
US3897905A (en) 1973-10-19 1975-08-05 Universal Oil Prod Co Electrostatic spraying nozzle
US3930061A (en) 1974-04-08 1975-12-30 Ransburg Corp Electrostatic method for forming structures and articles
GB1527592A (en) 1974-08-05 1978-10-04 Ici Ltd Wound dressing
JPS5926352B2 (en) * 1976-02-13 1984-06-26 関西ペイント株式会社 Electrostatic powder coating method
CA1109545A (en) * 1976-05-08 1981-09-22 Nissan Motor Co., Ltd. Electrostatic apparatus for controlling flow rate of liquid
CA1106032A (en) 1976-05-29 1981-07-28 Nissan Motor Co., Ltd. Method for controlling electrostatic fuel injectors
GB1569707A (en) 1976-07-15 1980-06-18 Ici Ltd Atomisation of liquids
IE45426B1 (en) 1976-07-15 1982-08-25 Ici Ltd Atomisation of liquids
US4073002A (en) 1976-11-02 1978-02-07 Ppg Industries, Inc. Self-adjusting power supply for induction charging electrodes
US4255777A (en) * 1977-11-21 1981-03-10 Exxon Research & Engineering Co. Electrostatic atomizing device
GB2018627B (en) 1978-04-17 1982-04-15 Ici Ltd Process and apparatus for spraying liguid
ZA791659B (en) 1978-04-17 1980-04-30 Ici Ltd Process and apparatus for spraying liquid
EP0005035B1 (en) 1978-04-19 1981-09-23 Imperial Chemical Industries Plc A method of preparing a tubular product by electrostatic spinning
US4198781A (en) * 1978-08-03 1980-04-22 Lasco, Inc. Plant destruction utilizing electrically conductive liquid
US4186886A (en) 1978-08-04 1980-02-05 Ppg Industries, Inc. Adapting means providing detachable mounting of an induction-charging adapter head on a spray device
GB2030060B (en) * 1978-09-26 1982-12-01 Ici Ltd Electrostatic spraying of liquid
US4266721A (en) 1979-09-17 1981-05-12 Ppg Industries, Inc. Spray application of coating compositions utilizing induction and corona charging means
ATE10711T1 (en) 1979-11-19 1984-12-15 Imperial Chemical Industries Plc ELECTROSTATIC SPRAYER.
DE3069312D1 (en) * 1979-12-21 1984-10-31 Ici Plc Containers and holders therefor for use in electrostatic spraying
DE3036814C2 (en) 1980-09-30 1984-10-04 Fa. Carl Freudenberg, 6940 Weinheim Wound compresses and process for their manufacture
ATE11232T1 (en) * 1980-11-11 1985-02-15 Imperial Chemical Industries Plc VESSEL FOR USE IN ELECTROSTATIC ATOMIZATION.
DE3042745C2 (en) 1980-11-13 1982-09-30 Philips Patentverwaltung Gmbh, 2000 Hamburg Magnetic tape cassette device with at least two push buttons
EP0058472B1 (en) 1981-02-12 1986-04-23 Imperial Chemical Industries Plc Agricultural spraying apparatus and containers for use therewith
JPS6057907B2 (en) * 1981-06-18 1985-12-17 工業技術院長 Liquid mixing and atomization method
SU1005939A1 (en) 1981-06-29 1983-03-23 Уральский научно-исследовательский институт трубной промышленности Ac electrostatic depositing of powder materials
US4439980A (en) 1981-11-16 1984-04-03 The United States Of America As Represented By The Secretary Of The Navy Electrohydrodynamic (EHD) control of fuel injection in gas turbines
EP0102713B1 (en) * 1982-08-25 1987-09-02 Imperial Chemical Industries Plc Electrostatic entrainment pump for a spraying system
GB2128900B (en) * 1982-10-29 1985-11-20 Theoktiste Christofidis Ionising spray
EP0121288B1 (en) 1983-01-06 1989-05-17 National Research Development Corporation Electrostatic spray head
EP0120633B1 (en) * 1983-03-25 1988-12-14 Imperial Chemical Industries Plc Spraying apparatus
US4509694A (en) 1983-06-01 1985-04-09 Canadian Patents & Development Limited Cross-current airfoil electrostatic nozzle
NZ209210A (en) 1983-08-18 1988-04-29 Ici Plc Electrostatic sprayhead atomises aqueous liquids
US4657793A (en) 1984-07-16 1987-04-14 Ethicon, Inc. Fibrous structures
GB8432272D0 (en) * 1984-12-20 1985-01-30 Ici Plc Spraying apparatus
GB8504254D0 (en) 1985-02-19 1985-03-20 Ici Plc Spraying apparatus
DE3661121D1 (en) * 1985-09-03 1988-12-15 Sale Tilney Technology Plc Electrostatic coating blade and method of electrostatic spraying
US4671289A (en) 1985-11-08 1987-06-09 Renco Corporation Housing for ultrasonic detector
GB8604328D0 (en) 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8609703D0 (en) 1986-04-21 1986-05-29 Ici Plc Electrostatic spraying
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
GB8614564D0 (en) 1986-06-16 1986-07-23 Ici Plc Spraying
US4748043A (en) 1986-08-29 1988-05-31 Minnesota Mining And Manufacturing Company Electrospray coating process
US4749125A (en) 1987-01-16 1988-06-07 Terronics Development Corp. Nozzle method and apparatus
DE3707547A1 (en) * 1987-03-10 1988-09-22 Bayer Ag METHOD AND DEVICE FOR SPRAYING PLANT PROTECTIVE SOLUTIONS OR DISPERSIONS
US4779515A (en) 1987-05-15 1988-10-25 General Motors Corporation Vacuum brake booster with bayonet mount having snap-retained mounting arm
DD271611A3 (en) 1987-10-27 1989-09-13 Verkehrswesen Hochschule SPRAY GUN WITH ELECTRIC KINETIC POWDER RECHARGE
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device
US5267555A (en) 1988-07-01 1993-12-07 Philip Pajalich Apparatus and method for ionizing medication containing mists
DE3925749C1 (en) * 1989-08-03 1990-10-31 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US5044564A (en) 1989-11-21 1991-09-03 Sickles James E Electrostatic spray gun
DE4022393A1 (en) 1990-07-13 1992-01-23 Marquardt Klaus IONIZER FOR IONIZING OXYGEN IN OXYGEN THERAPY
ATE121970T1 (en) 1990-07-25 1995-05-15 Ici Plc ELECTROSTATIC SPRAY METHOD.
US5086972A (en) 1990-08-01 1992-02-11 Hughes Aircraft Company Enhanced electrostatic paint deposition method and apparatus
DE4106564C2 (en) 1991-03-01 1999-06-10 Bosch Gmbh Robert Device for the electrostatic atomization of liquids
US5196171A (en) 1991-03-11 1993-03-23 In-Vironmental Integrity, Inc. Electrostatic vapor/aerosol/air ion generator
US5282982A (en) 1991-07-12 1994-02-01 Wells John R Blood washing method
GB9115278D0 (en) 1991-07-15 1991-08-28 Unilever Plc Liquid spraying apparatus and method
GB9115277D0 (en) 1991-07-15 1991-08-28 Unilever Plc Spraying system
GB9115279D0 (en) 1991-07-15 1991-08-28 Unilever Plc Hair and scalp treatment system
GB9219636D0 (en) 1991-10-10 1992-10-28 Ici Plc Spraying of liquids
WO1994013266A1 (en) 1992-05-29 1994-06-23 The Regents Of The University Of California Novel electrostatic process for manufacturing coated transplants and products
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
GB9226717D0 (en) 1992-12-22 1993-02-17 Coffee Ronald A Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
US5402945A (en) * 1993-01-22 1995-04-04 Gervan Company International Method for spraying plants and apparatus for its practice
US5409162A (en) 1993-08-09 1995-04-25 Sickles; James E. Induction spray charging apparatus
GB9406171D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5483953A (en) 1995-04-08 1996-01-16 The United States Of America As Represented By The Secretary Of The Navy Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device

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CN1090208A (en) 1994-08-03
CA2150692C (en) 2006-09-05
AU685411B2 (en) 1998-01-22
US6318640B1 (en) 2001-11-20
DE69324499T2 (en) 1999-08-12
DK0671980T3 (en) 1999-10-25
DE69324499D1 (en) 1999-05-20
WO1994012285A3 (en) 1994-10-13
ES2130393T3 (en) 1999-07-01
AU718118B2 (en) 2000-04-06
TW242576B (en) 1995-03-11
KR100289783B1 (en) 2001-09-17
JPH08504126A (en) 1996-05-07
WO1994012285A2 (en) 1994-06-09
AU5570294A (en) 1994-06-22
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GB9225098D0 (en) 1993-01-20
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NZ258174A (en) 1997-03-24
EP0671980A1 (en) 1995-09-20
EP0671980B1 (en) 1999-04-14
GR3030735T3 (en) 1999-11-30
HK1012301A1 (en) 1999-07-30
AU6351398A (en) 1998-07-02
US6105877A (en) 2000-08-22
ZA938895B (en) 1995-03-31
CN1104262C (en) 2003-04-02

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