CA2147927A1 - Repetition pipette - Google Patents
Repetition pipetteInfo
- Publication number
- CA2147927A1 CA2147927A1 CA002147927A CA2147927A CA2147927A1 CA 2147927 A1 CA2147927 A1 CA 2147927A1 CA 002147927 A CA002147927 A CA 002147927A CA 2147927 A CA2147927 A CA 2147927A CA 2147927 A1 CA2147927 A1 CA 2147927A1
- Authority
- CA
- Canada
- Prior art keywords
- rack
- piston
- step width
- advancing
- actuating element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge
Landscapes
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Sampling And Sample Adjustment (AREA)
- Steroid Compounds (AREA)
- Liquid Developers In Electrophotography (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Materials For Photolithography (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Gyroscopes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention relates to A repetition pipette including a syringe receiving section for the mounting portion of a syringe, a receiving member having a piston receiving portion for the mounting portion of a syringe piston, piston returning means for moving said receiving member away from said syringe receiving portion, piston advancing means for advancing said receiving member towards said piston receiving portion, which piston advancing means comprises a rack connected to said receiving member, and actuating element movable along an actuation path, and a pawl pivotally mounted thereto, which pawl is moved into engagement with the toothing of the rack so as to drive the latter for an advancing step when the actuating element is advanced, and is moved out of engagement with the rack when the actuating element is returned, and step width adjusting means for adjusting the step width of the advancing step, the step width adjusting means comprising a withholding element displaceable along the rack by means of an adjust-ing element for preventing the pawl from engaging the rack, characterized by stroke limiting means controlled by the step width adjusting means so as to increase the stroke length of the actuating element when the step width in-creases and to decrease the stroke length of the actuating element when the step width decreases.
Description
~147927 A REPETITION PIPETTE
The present invention relates to a repetition pipette as defined in the introductory portion of claim 1.
A repetition pipette of this type has become known from German patent 29 26 691. In this pipette the syringe re-ceiving section is a U-shaped groove in a pipette housing into which a syringe flange can be inserted. In the receiv-ing section the syringe flange is biased by a compression spring towards the delivery opening. The syringe piston includes a cylindrical actuating portion adapted to be fixed in the receiving member by clamping means. Thè piston returning means comprises a lever which extends from the receiving member through a lateral housing slot. The piston can be withdrawn from the syringe by moving the lever away from the syringe receiving portion. The actuating element of the piston advancing means is an actuating lever which is pivotally mounted on the side of the rack which does not include any toothing. The actuating lever includes the pawl and an actuating end extending from the housing on the toothing side of the rack. The withholding element of the step width adjusting means is a tongue which covers the toothing of the rack more or less depending on the settings of a rotary knob. The tongue prevents a pawl from engaging the rack upon actuation of the lever when the tongue is in the covering range. In the other range the pawl engages the toothing so as to drive the latter and the piston connected thereto for one advancing step. As a result the width of the advancing step and the volume dispensed by the syringe are adjustable by the rotary knob.
The stroke of the actuating lever includes an idle stroke portion for preventing the pawl from engagement with the toothing by the tongue, and a work stroke portion for hav-ing the pawl engage the toothing. The idle stroke portion is the greater and the work stroke portion the smaller, the smaller the adjusted step width and the smaller the liquid volume are. The user has to pivot the actuating lever through the idle stroke portion (which is substantial for many settings) even so this does not displace the piston within the syringe.
The problem to be solved by the invention is to provide a repetition pipette the handling of which is simplified.
The solution of this problem according to the present in-vention has been defined in claim 1. Further developments of the invention are included in the dependent claims.
The repetition pipette of the present invention includes stroke limiting means for limiting the stroke of the ac-tuating element. The stroke limiting means is controlled by the step width adjusting means such that the stroke length is increased when the step width increases and is decreased when the step width decreases. It is ensured that the ac-tuating element is moved always for the total work stroke while the idle stroke is reduced for all adjusted step widths. As a result the actuation serves always mainly or exclusively to have the actuating element perform the work stroke, i.e. to displace the syringe piston. This simpli-fies the handling and the handling expenditure is adapted to the respective dosage volume. The stroke length corres-ponds to the respective work distance so that it is a measure for the dosage volume and is an additional indica-tion of the pipette setting for the user.
Preferably the stroke limiting means includes an abutment limiting the stroke of the actuating element at the begin-ing, which abutment is adjustable by the step width adjust-ing means both in the advancing and returning direction of the actuating element. For compensation of an increase of the idle stroke the abutment is adjusted in the advancing direction of the actuating element when the step width decreases. When the step width increases to provide for increased volumes of the dispensed liquid, the abutment is displaced in the returning direction of the actuating ele-ment so that a sufficient work stroke and, if desired, a predetermined idle stroke are available.
Preferably the abutment comprising a shoulder of the with-holding element is displaceable along the rack so as to provide for a practically constant idle stroke. The actua-tion stroke is decreased or increased corresponding to the work stroke adjusted by means of the withholding element.
Preferably the abutment is positioned so as to be spaced from a forward end of the withholding element. Upon actua-tion the pawl can cooperate with the withholding element for a certain idle stroke before it engages into the tooth-ing.
The withholding element can be a sleeve guided along the rack. Preferably, the abutment is a lateral shoulder of the sleeve.
According to a further development of the invention the actuating element extends transversely across one side of the rack. Furthermore, the withholding element may include the shoulder on this side of the rack. The actuating ele-ment may include a pair of parallel legs on opposite sides of the rack, and the withholding element may include the shoulders on both sides. Furthermore the actuating element may include a pivot mount on each side of the rack and an actuation end on the other side of the rack.
- 21~7927 _ 4 Finally, the invention provides that said withholding ele-ment includes a laterally projecting guide cam which is guided in a cam guide of an adjusting knob. This adjusting means of the withholding element is particularly advantage-ous when it is arranged to cause, at the same time, dis-placements of the abutment.
The rack may be a rod including a toothing; as an alter-native it may be formed as a threaded rod or as a rod in-cluding circumferential grooves.
Further details and advantageous of the invention may be seen from the following description of the accompanying drawings with reference to a prefered embodiment. In the drawings:
Fig. 1 is a longitudinal section of a repetition pipette including stroke limiting means;
Fig. 2 is a partial section transverse to the longit-tudinal section of Fig. 2 of the same repetition pipette;
Fig. 3 is a partial longitudinal section of the same re-petition pipette with a decreased work stroke to more clearly show the stroke limiting means.
The repetition pipette includes a housing 1 which has a middle portion 2 formed as a handle, a foot portion 3 and a head portion 4. The foot portion 3 includes a syringe re-ceiving section 5 for a syringe flange of a syringe 6 which is partially indicated by dash dotted lines. Furthermore the foot portion 3 is provided with an endwise inlet open-ing 7 for the syringe body.
The middle portion 2 has internally a guide 8 which slid-ingly receives a receiving member 9 for the actuating end of the syringe piston. The receiving member 9 includes -21~7927 not shown - clamping means by which the inserted actuated end can be fixed.
Furthermore the receiving member 9 includes a returning lever 10 extending from a slot 11 in the left hand side of the housing.
The receiving member 9, at its face 12 remote from the re-ceiving section 5, carries a rack 13 which extends through the middle portion 2 to the head portion 4 of the housing 1. The rack 13 has a flat cross-section which is provided with a saw-tooth-shaped toothing 14 along one narrow side.
The steeper flank of the toothing 14 is facing the head portion 4.
In the head portion 4 an actuating lever 17 is pivotally mounted on an axis 15 in a formation 16 on one side of the housing. The actuating lever 17 includes a pair of parallel legs 18, 18' and has an actuating end project from a slot 19 in the opposite side of the housing. Between the actuat-ing lever 17 and the housing 1 a traction spring 20 acts to bias the actuating lever towards the head portion 4.
On the side of the rack 13 opposite its axis 15 the actuat-ing lever 17 pivotally mounts a pawl 22 on a pin 21 between its legs 18, 18'; as shown in Fig. 1 the pawl~22 has its engaging end engage into the toothing 14. The pawl 22 is biased towards the rack 13 by means of a - not shown - leg spring supported against the pawl and the actuating lever 17.
A withholding element 23 which is formed as a sleeve ex-tends from the head portion 4 to the rack 13. The sleeve 23 has a withholding surface 24 cover a part of the toothing 14. It is displaceable along the rack 13. To this end it includes a pin 25 adjacent its end facing away from the _ 6 rack 13; the pin 25 engages into a cam surface 26 of a rotary knob 27 mounted to the head portion 4. The position of the sleeve 23 in the housing 1 and the extent for which it covers the toothing 14 can be adjusted by rotary move-ments of the rotary knob 27.
The sleeve 23 has at its lateral surfaces 28, 28' outwardly projecting shoulders 29, 29'. The shoulders 29, 29' form abutments for the parallel legs 18, 18' of the lever 18 which receive between them the sleeve 23 and, respectively, the rack 13. The abutments 29, 29' include tapers 30, 30' towards the lever 17 so as to ensure positive engagement of the legs 18, 18'.
The repetition pipette operates as follows:
Initially a syringe 6 is moved through the inlet opening 7 so that its flange is inserted in the syringe receiving se~ction 5 and its actuating end is inserted in the receiv-ing member 9. By not shown clamping means it is fixed with-in the syringe receiving section 5 and the receiving member 9. For loading the syringe 6 the receiving member 9 can be displaced in a rearward direction R by means of the return-ing lever 10. Figs. 1 to 3 show the repetition pipette with its retracted receiving member 9 in a position ready for dispensing liquid.
In Figs 1 and 2 the sleeve 23 has been m~xim~lly retracted in the returning direction R by means of the rotary knob 27. The actuating lever 17 has been pivoted in the rearward direction by the traction spring as far as it is enabled by the slot 19 in the housing 1. The pawl 22 is still support-ed against the withholding surface 24 of the sleeve 23.
When the actuating lever 17 is actuated, the pawl 22 en-gages via the forward end of the sleeve 23 directly into the toothing 14 so as to drive the rack 13 in the advancing ~_ 7 direction V. Substantially the complete actuation stroke B
of the actuating lever 17 is used as work stroke for driv-ing the rack 13 and the dosing of liquid. After the actuat-ing lever 17 has been released it is automatically returned under the influence of the traction spring 20 to the shown original position, with the pawl 22 being disengaged from the toothing 14. The pipette is know ready for a further dosing step.
In Fig. 3 the sleeve 23 has been displaced m~Xim-lly across the toothing 13 by adjustment of the rotary knob 27. Only four teeth of the toothing 14 are accessible to be engaged by the pawl 22. The actuating lever 17 has its legs 18, 18' engage the shoulders 29, 29' of the sleeve 23 so as to be urged in the advancing direction V. The spacing of the abutments 29, 29' from the forward end of the sleeve 23 is dimensioned such that the pawl 22 is supported upon the withholding surface 24 in spaced relationship to its for-warrd end corresponding to an idle stroke. When the actuat-ing lever 17 is actuated initially the pawl 22 slides across the withholding surface 24 and is prevented thereby from engagement with the toothing so as to perform an idle stroke. The r~m~ining part of the actuation stroke B is accompanied by engagement of the pawl into the toothing 14 so as to be used as work stroke. A comparison with Fig. 1 shows that adjusting a smaller step width results in a substantially reduced actuation stroke B.
Adjustments between the shown extreme positions cause the actuation stroke to be changed proportionally to the work stroke. The idle stroke is substantially constant - as long as the lever 17 is not retained by the limitation of the slot 19 - and is determined by the spacings of the abut-ments 29, 29' from the forward end of the sleeve 23.
The present invention relates to a repetition pipette as defined in the introductory portion of claim 1.
A repetition pipette of this type has become known from German patent 29 26 691. In this pipette the syringe re-ceiving section is a U-shaped groove in a pipette housing into which a syringe flange can be inserted. In the receiv-ing section the syringe flange is biased by a compression spring towards the delivery opening. The syringe piston includes a cylindrical actuating portion adapted to be fixed in the receiving member by clamping means. Thè piston returning means comprises a lever which extends from the receiving member through a lateral housing slot. The piston can be withdrawn from the syringe by moving the lever away from the syringe receiving portion. The actuating element of the piston advancing means is an actuating lever which is pivotally mounted on the side of the rack which does not include any toothing. The actuating lever includes the pawl and an actuating end extending from the housing on the toothing side of the rack. The withholding element of the step width adjusting means is a tongue which covers the toothing of the rack more or less depending on the settings of a rotary knob. The tongue prevents a pawl from engaging the rack upon actuation of the lever when the tongue is in the covering range. In the other range the pawl engages the toothing so as to drive the latter and the piston connected thereto for one advancing step. As a result the width of the advancing step and the volume dispensed by the syringe are adjustable by the rotary knob.
The stroke of the actuating lever includes an idle stroke portion for preventing the pawl from engagement with the toothing by the tongue, and a work stroke portion for hav-ing the pawl engage the toothing. The idle stroke portion is the greater and the work stroke portion the smaller, the smaller the adjusted step width and the smaller the liquid volume are. The user has to pivot the actuating lever through the idle stroke portion (which is substantial for many settings) even so this does not displace the piston within the syringe.
The problem to be solved by the invention is to provide a repetition pipette the handling of which is simplified.
The solution of this problem according to the present in-vention has been defined in claim 1. Further developments of the invention are included in the dependent claims.
The repetition pipette of the present invention includes stroke limiting means for limiting the stroke of the ac-tuating element. The stroke limiting means is controlled by the step width adjusting means such that the stroke length is increased when the step width increases and is decreased when the step width decreases. It is ensured that the ac-tuating element is moved always for the total work stroke while the idle stroke is reduced for all adjusted step widths. As a result the actuation serves always mainly or exclusively to have the actuating element perform the work stroke, i.e. to displace the syringe piston. This simpli-fies the handling and the handling expenditure is adapted to the respective dosage volume. The stroke length corres-ponds to the respective work distance so that it is a measure for the dosage volume and is an additional indica-tion of the pipette setting for the user.
Preferably the stroke limiting means includes an abutment limiting the stroke of the actuating element at the begin-ing, which abutment is adjustable by the step width adjust-ing means both in the advancing and returning direction of the actuating element. For compensation of an increase of the idle stroke the abutment is adjusted in the advancing direction of the actuating element when the step width decreases. When the step width increases to provide for increased volumes of the dispensed liquid, the abutment is displaced in the returning direction of the actuating ele-ment so that a sufficient work stroke and, if desired, a predetermined idle stroke are available.
Preferably the abutment comprising a shoulder of the with-holding element is displaceable along the rack so as to provide for a practically constant idle stroke. The actua-tion stroke is decreased or increased corresponding to the work stroke adjusted by means of the withholding element.
Preferably the abutment is positioned so as to be spaced from a forward end of the withholding element. Upon actua-tion the pawl can cooperate with the withholding element for a certain idle stroke before it engages into the tooth-ing.
The withholding element can be a sleeve guided along the rack. Preferably, the abutment is a lateral shoulder of the sleeve.
According to a further development of the invention the actuating element extends transversely across one side of the rack. Furthermore, the withholding element may include the shoulder on this side of the rack. The actuating ele-ment may include a pair of parallel legs on opposite sides of the rack, and the withholding element may include the shoulders on both sides. Furthermore the actuating element may include a pivot mount on each side of the rack and an actuation end on the other side of the rack.
- 21~7927 _ 4 Finally, the invention provides that said withholding ele-ment includes a laterally projecting guide cam which is guided in a cam guide of an adjusting knob. This adjusting means of the withholding element is particularly advantage-ous when it is arranged to cause, at the same time, dis-placements of the abutment.
The rack may be a rod including a toothing; as an alter-native it may be formed as a threaded rod or as a rod in-cluding circumferential grooves.
Further details and advantageous of the invention may be seen from the following description of the accompanying drawings with reference to a prefered embodiment. In the drawings:
Fig. 1 is a longitudinal section of a repetition pipette including stroke limiting means;
Fig. 2 is a partial section transverse to the longit-tudinal section of Fig. 2 of the same repetition pipette;
Fig. 3 is a partial longitudinal section of the same re-petition pipette with a decreased work stroke to more clearly show the stroke limiting means.
The repetition pipette includes a housing 1 which has a middle portion 2 formed as a handle, a foot portion 3 and a head portion 4. The foot portion 3 includes a syringe re-ceiving section 5 for a syringe flange of a syringe 6 which is partially indicated by dash dotted lines. Furthermore the foot portion 3 is provided with an endwise inlet open-ing 7 for the syringe body.
The middle portion 2 has internally a guide 8 which slid-ingly receives a receiving member 9 for the actuating end of the syringe piston. The receiving member 9 includes -21~7927 not shown - clamping means by which the inserted actuated end can be fixed.
Furthermore the receiving member 9 includes a returning lever 10 extending from a slot 11 in the left hand side of the housing.
The receiving member 9, at its face 12 remote from the re-ceiving section 5, carries a rack 13 which extends through the middle portion 2 to the head portion 4 of the housing 1. The rack 13 has a flat cross-section which is provided with a saw-tooth-shaped toothing 14 along one narrow side.
The steeper flank of the toothing 14 is facing the head portion 4.
In the head portion 4 an actuating lever 17 is pivotally mounted on an axis 15 in a formation 16 on one side of the housing. The actuating lever 17 includes a pair of parallel legs 18, 18' and has an actuating end project from a slot 19 in the opposite side of the housing. Between the actuat-ing lever 17 and the housing 1 a traction spring 20 acts to bias the actuating lever towards the head portion 4.
On the side of the rack 13 opposite its axis 15 the actuat-ing lever 17 pivotally mounts a pawl 22 on a pin 21 between its legs 18, 18'; as shown in Fig. 1 the pawl~22 has its engaging end engage into the toothing 14. The pawl 22 is biased towards the rack 13 by means of a - not shown - leg spring supported against the pawl and the actuating lever 17.
A withholding element 23 which is formed as a sleeve ex-tends from the head portion 4 to the rack 13. The sleeve 23 has a withholding surface 24 cover a part of the toothing 14. It is displaceable along the rack 13. To this end it includes a pin 25 adjacent its end facing away from the _ 6 rack 13; the pin 25 engages into a cam surface 26 of a rotary knob 27 mounted to the head portion 4. The position of the sleeve 23 in the housing 1 and the extent for which it covers the toothing 14 can be adjusted by rotary move-ments of the rotary knob 27.
The sleeve 23 has at its lateral surfaces 28, 28' outwardly projecting shoulders 29, 29'. The shoulders 29, 29' form abutments for the parallel legs 18, 18' of the lever 18 which receive between them the sleeve 23 and, respectively, the rack 13. The abutments 29, 29' include tapers 30, 30' towards the lever 17 so as to ensure positive engagement of the legs 18, 18'.
The repetition pipette operates as follows:
Initially a syringe 6 is moved through the inlet opening 7 so that its flange is inserted in the syringe receiving se~ction 5 and its actuating end is inserted in the receiv-ing member 9. By not shown clamping means it is fixed with-in the syringe receiving section 5 and the receiving member 9. For loading the syringe 6 the receiving member 9 can be displaced in a rearward direction R by means of the return-ing lever 10. Figs. 1 to 3 show the repetition pipette with its retracted receiving member 9 in a position ready for dispensing liquid.
In Figs 1 and 2 the sleeve 23 has been m~xim~lly retracted in the returning direction R by means of the rotary knob 27. The actuating lever 17 has been pivoted in the rearward direction by the traction spring as far as it is enabled by the slot 19 in the housing 1. The pawl 22 is still support-ed against the withholding surface 24 of the sleeve 23.
When the actuating lever 17 is actuated, the pawl 22 en-gages via the forward end of the sleeve 23 directly into the toothing 14 so as to drive the rack 13 in the advancing ~_ 7 direction V. Substantially the complete actuation stroke B
of the actuating lever 17 is used as work stroke for driv-ing the rack 13 and the dosing of liquid. After the actuat-ing lever 17 has been released it is automatically returned under the influence of the traction spring 20 to the shown original position, with the pawl 22 being disengaged from the toothing 14. The pipette is know ready for a further dosing step.
In Fig. 3 the sleeve 23 has been displaced m~Xim-lly across the toothing 13 by adjustment of the rotary knob 27. Only four teeth of the toothing 14 are accessible to be engaged by the pawl 22. The actuating lever 17 has its legs 18, 18' engage the shoulders 29, 29' of the sleeve 23 so as to be urged in the advancing direction V. The spacing of the abutments 29, 29' from the forward end of the sleeve 23 is dimensioned such that the pawl 22 is supported upon the withholding surface 24 in spaced relationship to its for-warrd end corresponding to an idle stroke. When the actuat-ing lever 17 is actuated initially the pawl 22 slides across the withholding surface 24 and is prevented thereby from engagement with the toothing so as to perform an idle stroke. The r~m~ining part of the actuation stroke B is accompanied by engagement of the pawl into the toothing 14 so as to be used as work stroke. A comparison with Fig. 1 shows that adjusting a smaller step width results in a substantially reduced actuation stroke B.
Adjustments between the shown extreme positions cause the actuation stroke to be changed proportionally to the work stroke. The idle stroke is substantially constant - as long as the lever 17 is not retained by the limitation of the slot 19 - and is determined by the spacings of the abut-ments 29, 29' from the forward end of the sleeve 23.
Claims (8)
1. A repetition pipette including a syringe receiving section (5) for the mounting portion of a syringe (6), a receiving member (9) having a piston receiving portion for the mounting portion of a syringe piston, piston returning means (10) for moving said receiving member away from said syringe receiving portion, piston advancing means (13,17, 22) for advancing said receiving member towards said piston receiving portion, which piston advancing means comprises a rack (13) connected to said receiving member, and an ac-tuating element (17) movable along an actuation path (B), and a pawl (22) pivotally mounted thereto, which pawl is moved into engagement with the toothing (14) of the rack so as to drive the latter for an advancing step when the ac-tuating element is advanced, and is moved out of engagement with the rack when the actuating element is returned, and step width adjusting means (23,27) for adjusting the step width of the advancing step, the step width adjusting means comprising a withholding element (23) displaceable along the rack by means of an adjusting element (27) for prevent-ing the pawl from engaging the rack, characterized by stroke limiting means (29,29') controlled by the step width adjusting means (23,27) so as to increase the stroke length (B) of the actuating element (17) when the step width in-creases and to decrease the stroke length of the actuating element when the step width decreases.
2. A pipette according to claim 1, wherein said stroke limiting means includes an abutment (29,29') limiting the stroke (B) of the actuating element (17) at the beginning, which abutment is adjustable by the step width adjusting means (23,27) both in the advancing and returning direction (V and R) of the actuating element.
3. A pipette according to claim 2, wherein the abut-ment comprises a lateral shoulder (29,29') of the withhold-ing element (23).
4. A pipette according to claim 1, wherein said with-holding element comprises a sleeve (23) guided along the rack (13).
5. A pipette according to claim 3 or claim 4, wherein said actuating element (17) includes a leg (18,18') extend-ing transversely across one side of said rack (13) and the withholding element (23) has said shoulder (29) on the same side of the rack (13).
6. A pipette according to claim 5, wherein said actuating element (17) has a pair of parallel legs (18,18') on opposite sides of the rack (13) and the withholding element (23) includes shoulders (29,29') associated with the legs on respective sides (28,28') of the withholding element.
7. A pipette according to claim 5 or claim 6, wherein said actuating element (17) includes a pivot mount (15) on one side of the rack (13) and an actuating end on the other side of the rack.
8. A pipette according to claim 1, wherein said with-holding element (23) includes a laterally projecting guide cam (25) which is guided in a cam guide (26) of an adjust-ing knob (27).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4414744A DE4414744C1 (en) | 1994-04-27 | 1994-04-27 | Repeater pipette |
| DEP4414744.9 | 1994-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2147927A1 true CA2147927A1 (en) | 1995-10-28 |
Family
ID=6516601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002147927A Abandoned CA2147927A1 (en) | 1994-04-27 | 1995-04-26 | Repetition pipette |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5573729A (en) |
| EP (1) | EP0679440B1 (en) |
| JP (1) | JPH08150207A (en) |
| AT (1) | ATE163573T1 (en) |
| CA (1) | CA2147927A1 (en) |
| DE (2) | DE4414744C1 (en) |
| FI (1) | FI116202B (en) |
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|---|---|---|---|---|
| JP2838070B2 (en) * | 1996-03-07 | 1998-12-16 | 株式会社ニチリョー | Repetitive pipette |
| DE20019821U1 (en) * | 1999-12-09 | 2001-06-07 | Brand Gmbh & Co Kg | Dosing device for liquids |
| US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| JP4148894B2 (en) | 2001-10-16 | 2008-09-10 | マトリックス・テクノロジイズ・コーポレーション | Hand-held pipette |
| US7284454B2 (en) * | 2004-05-27 | 2007-10-23 | Matrix Technologies Corporation | Hand held pipette |
| US20060027033A1 (en) * | 2002-10-16 | 2006-02-09 | Richard Cote | Hand-held pipette employing voice recognition control |
| US7381371B2 (en) * | 2004-01-16 | 2008-06-03 | Heathrow Scientific Llc | Pipette device with pivotable nozzle assembly |
| EP1804865B1 (en) | 2004-10-21 | 2009-09-30 | Novo Nordisk A/S | Dial-down mechanism for wind-up pen |
| US20090043264A1 (en) | 2005-04-24 | 2009-02-12 | Novo Nordisk A/S | Injection Device |
| EP1996260B1 (en) * | 2006-03-10 | 2015-09-23 | Novo Nordisk A/S | An injection device having a gearing arrangement |
| EP1996259B1 (en) | 2006-03-10 | 2012-08-15 | Novo Nordisk A/S | An injection device and a method of changing a cartridge in the device |
| ATE458517T1 (en) | 2006-05-16 | 2010-03-15 | Novo Nordisk As | TRANSMISSION MECHANISM FOR AN INJECTION DEVICE |
| JP5253387B2 (en) | 2006-05-18 | 2013-07-31 | ノボ・ノルデイスク・エー／エス | Injection device with mode locking means |
| AU2008231897B2 (en) | 2007-03-23 | 2012-11-29 | Novo Nordisk A/S | An injection device comprising a locking nut |
| DK2496292T3 (en) * | 2009-11-06 | 2014-10-06 | Shl Group Ab | DEVICE FOR MEDICINE DELIVERY |
| DE202010009747U1 (en) * | 2010-07-01 | 2010-11-18 | Brand Gmbh + Co Kg | Pipette for a pipette system with pipette and syringe |
| MX2014007375A (en) | 2011-12-29 | 2014-08-22 | Novo Nordisk As | Torsion- spring based wind-up autoinjector pen with dial - up/dial - down dosing mechanism. |
| WO2014204587A1 (en) * | 2013-06-17 | 2014-12-24 | Waters Technologies Corporation | Micropipet for aliquoting small volumes of fluid |
| US10532355B2 (en) | 2015-06-05 | 2020-01-14 | Mimetas B.V. | Microfluidic plate |
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|---|---|---|---|---|
| US2768768A (en) * | 1953-02-27 | 1956-10-30 | Gibson Homans Company | Calking gun |
| NL107751C (en) * | 1958-03-22 | |||
| US3110310A (en) * | 1961-07-20 | 1963-11-12 | Ideal Instr & Mfg Co Inc | Metering hypodermic syringe |
| US3141583A (en) * | 1962-03-23 | 1964-07-21 | William L Brickson | Injection gun |
| US3606085A (en) * | 1968-08-26 | 1971-09-20 | Ian Butler Spilman | Dispensing gun for pastes and like substances |
| DE2926691C2 (en) * | 1979-07-02 | 1983-05-26 | Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg | Repeater pipette |
| US4099548A (en) * | 1976-08-25 | 1978-07-11 | Oxford Laboratories Inc. | Hand-held pipette for repetitively dispensing precise volumes of liquid |
| FI58875C (en) * | 1979-08-31 | 1981-05-11 | Suovaniemi Finnpipette | pipette |
| DE3204178C2 (en) * | 1982-02-06 | 1986-03-20 | Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg | Pipetting device |
| US4467942A (en) * | 1982-04-29 | 1984-08-28 | Yuuji Oshikubo | Repeating dispenser |
| DE3216644A1 (en) * | 1982-05-04 | 1983-11-10 | Nichiryo Co., Ltd., Tokyo | Repeat dispenser |
| EP0109913A3 (en) * | 1982-11-03 | 1984-09-12 | Micro-Mega | Dental syringe for intra-ligament injections |
| FI921648A0 (en) * | 1992-04-13 | 1992-04-13 | Labsystems Oy | STEGPIPETT. |
| US5323931A (en) * | 1993-02-08 | 1994-06-28 | Prince Castle Inc. | Dispenser for extrudable material including dispensing from collapsible containers |
-
1994
- 1994-04-27 DE DE4414744A patent/DE4414744C1/en not_active Expired - Lifetime
-
1995
- 1995-03-24 DE DE59501519T patent/DE59501519D1/en not_active Expired - Fee Related
- 1995-03-24 AT AT95104357T patent/ATE163573T1/en active
- 1995-03-24 EP EP95104357A patent/EP0679440B1/en not_active Expired - Lifetime
- 1995-04-20 US US08/425,521 patent/US5573729A/en not_active Expired - Lifetime
- 1995-04-26 FI FI951977A patent/FI116202B/en not_active IP Right Cessation
- 1995-04-26 CA CA002147927A patent/CA2147927A1/en not_active Abandoned
- 1995-04-26 JP JP7127179A patent/JPH08150207A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE4414744C1 (en) | 1995-11-02 |
| EP0679440B1 (en) | 1998-03-04 |
| FI951977A0 (en) | 1995-04-26 |
| ATE163573T1 (en) | 1998-03-15 |
| JPH08150207A (en) | 1996-06-11 |
| FI951977A (en) | 1995-10-28 |
| DE59501519D1 (en) | 1998-04-09 |
| EP0679440A1 (en) | 1995-11-02 |
| FI116202B (en) | 2005-10-14 |
| US5573729A (en) | 1996-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |