CA2109960A1 - Thromboresistant coating for defoaming applications - Google Patents

Thromboresistant coating for defoaming applications

Info

Publication number
CA2109960A1
CA2109960A1 CA 2109960 CA2109960A CA2109960A1 CA 2109960 A1 CA2109960 A1 CA 2109960A1 CA 2109960 CA2109960 CA 2109960 CA 2109960 A CA2109960 A CA 2109960A CA 2109960 A1 CA2109960 A1 CA 2109960A1
Authority
CA
Canada
Prior art keywords
mixture
anticoagulant
heparin
coating
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2109960
Other languages
French (fr)
Other versions
CA2109960C (en
Inventor
Li-Chien Hsu
Mark Loar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edwards Lifesciences Corp
Original Assignee
Li-Chien Hsu
Mark Loar
Baxter International Inc.
Edwards Lifesciences Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Li-Chien Hsu, Mark Loar, Baxter International Inc., Edwards Lifesciences Corporation filed Critical Li-Chien Hsu
Publication of CA2109960A1 publication Critical patent/CA2109960A1/en
Application granted granted Critical
Publication of CA2109960C publication Critical patent/CA2109960C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate

Abstract

ABSTRACT
A composition for coating medical blood contacting surfaces comprises a mixture of an anticoagulant and a defoaming agent. The coating composition is applied by either dipping the device into a solution containing the mixture or by spraying the mixture onto the surface.
Alternatively, the surface can be sequentially dip coated and/or sprayed with the individual components. In a preferred embodiment, the anticoagulant is a quaternary ammonium complex of heparin, preferably stearyldimethylbenzyl ammonium heparin, and the antifoaming agent is a mixture of polydimethylsiloxane and silicone dioxide.
CA002109960A 1991-05-31 1992-05-20 Thromboresistant coating for defoaming applications Expired - Lifetime CA2109960C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70860391A 1991-05-31 1991-05-31
US708,603 1991-05-31
PCT/US1992/004268 WO1992021387A1 (en) 1991-05-31 1992-05-20 Thromboresistant coating for defoaming applications

Publications (2)

Publication Number Publication Date
CA2109960A1 true CA2109960A1 (en) 1992-12-10
CA2109960C CA2109960C (en) 2000-07-18

Family

ID=24846460

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002109960A Expired - Lifetime CA2109960C (en) 1991-05-31 1992-05-20 Thromboresistant coating for defoaming applications

Country Status (6)

Country Link
US (1) US5541167A (en)
EP (1) EP0588895B1 (en)
JP (1) JP2858045B2 (en)
CA (1) CA2109960C (en)
DE (1) DE69201193T2 (en)
WO (1) WO1992021387A1 (en)

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US8101196B2 (en) * 2001-06-26 2012-01-24 Biointeractions, Ltd. Polysaccharide biomaterials and methods of use thereof
US6558409B1 (en) 2001-09-28 2003-05-06 Tyco Healthcare Group Lp Plasma treated surgical needles and methods for their manufacture
US7294357B2 (en) * 2001-09-28 2007-11-13 Tyco Healthcare Group Lp Plasma coated sutures
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US8216045B2 (en) * 2004-01-27 2012-07-10 Integrated Group Assets Inc. Method and apparatus for providing a lottery
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Also Published As

Publication number Publication date
JP2858045B2 (en) 1999-02-17
EP0588895B1 (en) 1995-01-11
DE69201193D1 (en) 1995-02-23
WO1992021387A1 (en) 1992-12-10
DE69201193T2 (en) 1995-09-07
EP0588895A1 (en) 1994-03-30
JPH06507808A (en) 1994-09-08
US5541167A (en) 1996-07-30
CA2109960C (en) 2000-07-18

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