CA2102778A1 - Nouvelles compositions a base de derives de la classe des taxanes - Google Patents
Nouvelles compositions a base de derives de la classe des taxanesInfo
- Publication number
- CA2102778A1 CA2102778A1 CA002102778A CA2102778A CA2102778A1 CA 2102778 A1 CA2102778 A1 CA 2102778A1 CA 002102778 A CA002102778 A CA 002102778A CA 2102778 A CA2102778 A CA 2102778A CA 2102778 A1 CA2102778 A1 CA 2102778A1
- Authority
- CA
- Canada
- Prior art keywords
- compositions based
- novel compositions
- taxane class
- derivatives
- class derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000001802 infusion Methods 0.000 abstract 1
- 229950008882 polysorbate Drugs 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Paints Or Removers (AREA)
- Saccharide Compounds (AREA)
Abstract
2102778 9300929 PCTABS00161 La présente invention concerne de nouvelles compositions à base de dérivés de la classe des taxanes constituées de solutions de ces dérivés dans un mélange de solvant composé d'éthanol et de polysorbate. Ces solutions sont utilisées pour préparer des perfusions.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9108527A FR2678833B1 (fr) | 1991-07-08 | 1991-07-08 | Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes. |
FR9108527 | 1991-07-08 | ||
PCT/FR1992/000625 WO1993000929A1 (fr) | 1991-07-08 | 1992-07-03 | Nouvelles compositions a base de derives de la classe des taxanes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2102778A1 true CA2102778A1 (fr) | 1993-01-09 |
CA2102778C CA2102778C (fr) | 2004-04-20 |
Family
ID=9414814
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002102778A Expired - Lifetime CA2102778C (fr) | 1991-07-08 | 1992-07-03 | Nouvelles compositions a base de derives de la classe des taxanes |
CA002102777A Expired - Lifetime CA2102777C (fr) | 1991-07-08 | 1992-07-03 | Nouvelles compositions a base de derives de la classe des taxanes |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002102777A Expired - Lifetime CA2102777C (fr) | 1991-07-08 | 1992-07-03 | Nouvelles compositions a base de derives de la classe des taxanes |
Country Status (28)
Country | Link |
---|---|
US (1) | US5403858A (fr) |
EP (4) | EP0593601B1 (fr) |
JP (2) | JPH06507914A (fr) |
KR (1) | KR0136722B1 (fr) |
AT (2) | ATE147992T1 (fr) |
CA (2) | CA2102778C (fr) |
CZ (1) | CZ280965B6 (fr) |
DE (3) | DE69223624T2 (fr) |
DK (2) | DK0593601T3 (fr) |
ES (2) | ES2110003T3 (fr) |
FI (2) | FI111807B (fr) |
FR (1) | FR2678833B1 (fr) |
GE (1) | GEP19991517B (fr) |
GR (2) | GR3022355T3 (fr) |
HK (1) | HK1006207A1 (fr) |
HU (1) | HU217839B (fr) |
IE (2) | IE80461B1 (fr) |
MX (2) | MX9203959A (fr) |
NO (2) | NO307205B1 (fr) |
PL (1) | PL169372B1 (fr) |
RU (1) | RU2134123C1 (fr) |
SE (1) | SE0593656E5 (fr) |
SG (1) | SG80541A1 (fr) |
SK (1) | SK279946B6 (fr) |
TW (2) | TW495362B (fr) |
WO (2) | WO1993000928A1 (fr) |
YU (1) | YU48913B (fr) |
ZA (1) | ZA924999B (fr) |
Families Citing this family (109)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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CA2086874E (fr) * | 1992-08-03 | 2000-01-04 | Renzo Mauro Canetta | Methodes d'administration du taxol |
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US5684169A (en) * | 1992-11-27 | 1997-11-04 | Ensuiko Sugar Refining Co., Ltd. | Cyclodextrin inclusion complex of taxol, and method for its production and its use |
JPH06157330A (ja) * | 1992-11-27 | 1994-06-03 | Ensuiko Sugar Refining Co Ltd | タキソールのサイクロデキストリン包接物,その製造法と用途 |
FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
US5994341A (en) * | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
DK0797988T3 (da) * | 1993-07-19 | 2009-05-11 | Univ British Columbia | Anti-angiogene præparater og fremgangsmåder til anvendelse deraf |
US6335356B1 (en) | 1994-01-07 | 2002-01-01 | Sugen, Inc. | Method of treating a patient by parenteral administration of a lipophilic compound |
US5610173A (en) * | 1994-01-07 | 1997-03-11 | Sugen, Inc. | Formulations for lipophilic compounds |
WO1995033490A1 (fr) * | 1994-06-02 | 1995-12-14 | Enzon, Inc. | Procede de solubilisation de substances pratiquement insolubles dans l'eau |
WO1996003113A1 (fr) * | 1994-07-22 | 1996-02-08 | G.D. Searle & Co. | Systeme d'apport de medicaments auto-emulsifiant |
US5681846A (en) * | 1995-03-17 | 1997-10-28 | Board Of Regents, The University Of Texas System | Extended stability formulations for paclitaxel |
US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
AU724842B2 (en) * | 1995-12-21 | 2000-09-28 | Genelabs Technologies, Inc. | Taxane composition and method |
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WO2017214456A1 (fr) | 2016-06-08 | 2017-12-14 | Abbvie Inc. | Anticorps anti-cd98 et conjugués anticorps-médicament |
WO2017214335A1 (fr) | 2016-06-08 | 2017-12-14 | Abbvie Inc. | Anticorps anti-b7-h3 et conjugués anticorps-médicaments |
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EP3679925A4 (fr) | 2017-09-07 | 2021-04-21 | Shenzhen Salubris Pharmaceuticals Co. Ltd | Composition pharmaceutique de conjugué de docétaxel et procédé de préparation |
JP2018115178A (ja) * | 2018-03-15 | 2018-07-26 | ニプロ株式会社 | ドセタキセル製剤 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US4206221A (en) * | 1979-01-03 | 1980-06-03 | The United States Of America As Represented By The Secretary Of Agriculture | Cephalomannine and its use in treating leukemic tumors |
US4534899A (en) * | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
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1991
- 1991-07-08 FR FR9108527A patent/FR2678833B1/fr not_active Expired - Lifetime
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1992
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- 1992-07-03 RU RU94016875A patent/RU2134123C1/ru active Protection Beyond IP Right Term
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- 1992-07-03 WO PCT/FR1992/000625 patent/WO1993000929A1/fr active IP Right Grant
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- 1992-07-03 SG SG9607279A patent/SG80541A1/en unknown
- 1992-07-03 EP EP92401903A patent/EP0522937A1/fr active Pending
- 1992-07-03 PL PL92301949A patent/PL169372B1/pl unknown
- 1992-07-03 DK DK92914822.9T patent/DK0593601T3/da active
- 1992-07-03 ES ES92915686T patent/ES2096091T7/es active Active
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