CA2035492A1 - Liquid lavage/ventilation of the pulmonary system - Google Patents

Liquid lavage/ventilation of the pulmonary system

Info

Publication number
CA2035492A1
CA2035492A1 CA002035492A CA2035492A CA2035492A1 CA 2035492 A1 CA2035492 A1 CA 2035492A1 CA 002035492 A CA002035492 A CA 002035492A CA 2035492 A CA2035492 A CA 2035492A CA 2035492 A1 CA2035492 A1 CA 2035492A1
Authority
CA
Canada
Prior art keywords
liquid
ventilation
biologically active
perfluorocarbon
pulmonary system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002035492A
Other languages
French (fr)
Other versions
CA2035492C (en
Inventor
K. Michael Sekins
Thomas H. Shaffer
Marla R. Wolfson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alliance Pharmaceutical Corp
Temple University of Commonwealth System of Higher Education
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/495,817 external-priority patent/US5158536A/en
Application filed by Individual filed Critical Individual
Priority to CA002332618A priority Critical patent/CA2332618A1/en
Publication of CA2035492A1 publication Critical patent/CA2035492A1/en
Application granted granted Critical
Publication of CA2035492C publication Critical patent/CA2035492C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4272—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue

Abstract

The invention provides for the pulmonary administration of biologically active agents via liquid lavage/ventilation.
A liquid medium comprising at least one biologically active agent and a liquid carrier is passed through at least a portion of the patient's pulmonary air passages.
The liquid medium may be a breathable liquid, such as a perfluorocarbon liquid or physiological saline solution. Suitable perfluorocarbon liquids having the requisite physical and thermal properties are characterized by an average molecular weight in the range of from about 350 to about 560. Representative perfluorocarbon liquids are FC-84, FC-72, RM-82, FC-75, RM-101, and perfluorodecalin.
CA002035492A 1990-03-19 1991-02-01 Liquid lavage/ventilation of the pulmonary system Expired - Fee Related CA2035492C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002332618A CA2332618A1 (en) 1990-03-19 1991-02-01 Liquid lavage/ventilation of the pulmonary system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/495,817 US5158536A (en) 1989-08-28 1990-03-19 Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids
US495,817 1990-03-19

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002332618A Division CA2332618A1 (en) 1990-03-19 1991-02-01 Liquid lavage/ventilation of the pulmonary system

Publications (2)

Publication Number Publication Date
CA2035492A1 true CA2035492A1 (en) 1991-09-20
CA2035492C CA2035492C (en) 2001-03-27

Family

ID=23970103

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002035492A Expired - Fee Related CA2035492C (en) 1990-03-19 1991-02-01 Liquid lavage/ventilation of the pulmonary system

Country Status (1)

Country Link
CA (1) CA2035492C (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0650378A1 (en) * 1992-07-16 1995-05-03 Temple University of the Commonwealth System of Higher Education Treatment of physiological conditions with degassed perfluorocarbon liquid
EP1208851A3 (en) * 1991-11-14 2003-05-07 Alliance Pharmaceutical Corporation A medicament for pulmonary drug delivery
US7726311B2 (en) 2002-11-29 2010-06-01 Universite De Sherbrooke Method and apparatus for conducting total liquid ventilation with control of residual volume and ventilation cycle profile
CN114098699A (en) * 2021-11-05 2022-03-01 中国科学院精密测量科学与技术创新研究院 Experiment bed for magnetic resonance perfusion imaging of small animals

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1208851A3 (en) * 1991-11-14 2003-05-07 Alliance Pharmaceutical Corporation A medicament for pulmonary drug delivery
EP0650378A1 (en) * 1992-07-16 1995-05-03 Temple University of the Commonwealth System of Higher Education Treatment of physiological conditions with degassed perfluorocarbon liquid
EP0650378A4 (en) * 1992-07-16 1995-07-12 Univ Temple Treatment of physiological conditions with degassed perfluorocarbon liquid.
US7726311B2 (en) 2002-11-29 2010-06-01 Universite De Sherbrooke Method and apparatus for conducting total liquid ventilation with control of residual volume and ventilation cycle profile
CN114098699A (en) * 2021-11-05 2022-03-01 中国科学院精密测量科学与技术创新研究院 Experiment bed for magnetic resonance perfusion imaging of small animals

Also Published As

Publication number Publication date
CA2035492C (en) 2001-03-27

Similar Documents

Publication Publication Date Title
CA2090404A1 (en) Nonaqueous fluorinated drug delivery vehicle suspensions
US4378797A (en) Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
KR870006893A (en) Pharmaceutical formulations of highly viscous hydrogels or suspensions thereof
AU3275689A (en) Process for stabilizing human albumin solutions and the solution obtained
ATE92931T1 (en) FLUORINE AND PHOSPHORUS CONTAINING AMPHIPHILIC MOLECULES WITH SURFACE ACTIVE PROPERTIES.
DE68919146D1 (en) Selected strains of Lactobacillus containing pharmaceutical compositions.
KR970703130A (en) Fluticasone Propionate Formulations
CA2343123A1 (en) Active substance concentrate with formoterol, suitable for storage
IT1243745B (en) TRANSDERMAL THERAPEUTIC COMPOSITIONS CONTAINING DRUG AND / OR PROMOTING AGENT OF THE SKIN ABSORPTION SUPPORTED ON MICROPOROUS PARTICLES AND POLYMERIC MICROSPHERES AND THEIR PREPARATION.
HK1021622A1 (en) Preparation for the transport of an active substance across barriers
FR2624015B1 (en) MEDICINE COMPRISING THE COMBINATION OF COLISTINE, TOBRAMYCIN AND AMPHOTERICIN B VAPORIZED
CA2035492A1 (en) Liquid lavage/ventilation of the pulmonary system
CA2132841A1 (en) Aminocyclohexylamides for antiarrhythmic and anaesthetic uses
SE8400723D0 (en) PHARMACEUTICAL COMPOSITION
DE69329340T2 (en) STORAGE OF STEM CELLS
ATE104146T1 (en) DELAYED-RELEASE PREPARATION OF A HYDROCHLORIDE OF A BASIC DRUG.
SE9403905D0 (en) New formulations
WO1996020719A3 (en) Body fluid replacement solution
Nordback et al. Acute effects of a nucleoside analog dideoxyinosine (DDI) on the pancreas
Sakaguchi et al. Lipid Peroxide Formation and Membrane Damage in Endotoxicosis.
Korzun et al. Calculation of Thermodynamic Properties of Fe--Cr and Fe--Ni Liquid Solutions
Grimble et al. Nifuratel for trichomonal vaginitis.
Mitskovski et al. [Efficiency of some fungicides in controlling the parasite, Peronospora tabacini in tobacco plantations].[Macedonian]
Gilani et al. Cardiovascular changes associated with adrenaline infiltration during halothane anaesthesia.
Zinnemann Haemophilus aphrophilus endocarditis.

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed