CA1152408A - Method and apparatus for the treatment of ascites - Google Patents

Method and apparatus for the treatment of ascites

Info

Publication number
CA1152408A
CA1152408A CA000353261A CA353261A CA1152408A CA 1152408 A CA1152408 A CA 1152408A CA 000353261 A CA000353261 A CA 000353261A CA 353261 A CA353261 A CA 353261A CA 1152408 A CA1152408 A CA 1152408A
Authority
CA
Canada
Prior art keywords
patient
catheter
ascites
flexible
valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000353261A
Other languages
French (fr)
Inventor
Salomon Hakim
Carlos A. Hakim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hakim Co Ltd
Original Assignee
Hakim Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hakim Co Ltd filed Critical Hakim Co Ltd
Application granted granted Critical
Publication of CA1152408A publication Critical patent/CA1152408A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002Implant devices for drainage of body fluids from one part of the body to another

Abstract

ABSTRACT OF THE DISCLOSURE
In the method of treating ascites disclosed herein, an intraperitonal inlet tube is connected to an implanted jug-ular catheter through a valving unit including a pair of one-way valve units which are connected in series through a flexible intermediate chamber to another pair of one-way valve units. The flexible chamber is surgically secured near the surface of the patient's abdomen or chest, preferably over the sternum, so that, by manual pressure, the patient can periodically deform the con-duit thereby to effect pumping of the ascites fluid.

Description

~.~52408 The present invention relates to the treatment of asci-tes and more particularly such treatment ~y means of an implanted peritoneo - venous shunt, In the treatment of ascites, i.e, the accumulation of large amounts of fluid in theperitoneal cavity of the patient, it has previously been proposed to shunt or reroute ascitic fluid from the peritoneal cavity into the superior vena cava, the thoracic duct or the bladder. The providing of a shunt from the peritoneal cavity to the central venous system has offered many advantages over other types of treatment but certain difficulties have existed with prior devices and methods for effecting such treatment, The shunt devices proposed heretofore for such treat-ment have typically been either quite bulky, i.e. so as to require a mor~ ela~orate surgical procedure, or have ~een unduly subject to clogging by the presence of complex protein compounds in the ascitic fluid, Among the several objects of the present invention may be noted the provision of an improved peritoneovenous shunt which is highly resiatant to clogging; which is highly effective in the treatment of ascites; which is relatively easily implanted in a comparativel~ simple surgical procedure; which is of relatively si~ple and in~xpensive construction and which is highly reliable wh~^ch can ~e sterilized ~y autoclave without altering its inter~
nal mechanism. Other objects and features will be in part apparent and in part poin.ted out hereinafter, BRIEF DESCRIPTIO~ OF THE DRAWING
Fig. 1 is a schematic representation of a patient assumed to be suffering from ascites and illustrates the placement of the apparatus disclosed herein;

S ~S2408 1 Fig. 2 is a view, partially in section, of the overall arrangement of the shunt system disclosed herein;
Fig. 3 is a view, partially in section, of the construction of the shunt valve unit; and Fig. 4 is a side sectional view of the shunt valve disclosed herein, and appears on the same page as Figure 1.

BRIEF DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring n~w to Fig. 1 a patient,assumed to be suf-fering from ascites, is indicated generally by reference charac-ter 11. In accordance with the practice of the present invention - la -r p~ .

1 ~ r;;~408 1 a perforate inlet catheter 13 ~eritoneal catheter~ is surgically introduced into the peritoneal cavity of the pa~ient, through an a~dominal incision 14, so as to provide a means for drawing off accumulated ascitic fluid~ Peritoneal catheter 13 is con-nected ~y means of a strai~ht connector 12, and a proximal tu~e 15 to an antecham~er 17 and valve unit 1~ described in greater detail hereinafter, which is implanted in a su~cutaneous pocket surgically formed over the patient's sternum 16, Proximal tu~e 15, antecham~er 17, and the valve unit lQ are implanted through a subcutaneous tunnel in accordance with conventional surgical procedures. After passing through valve unit 19, the ascitic fluid is directed into the central venous system through the distal tube 20 and atrial catheter 22. In contrast with more conventional systems, the distal tu~e 20 and atrial catheter 22 are of relatively small diameter, This small diameter facilitates a simpler mode of implantation wherein the distal tu~e is led, through a subcutaneous tunnel up to the patient's neck where a small cervical incision is made 21, Working through this incis-ion 21, the atrial catheter 22 i9 inserted into the exterior jugular vein as indicated at 24. The length of the atrial cath-eter 22 is such to allow its tip to extend, from the point of introduction at the external jugular vein, down the superior vena cava into the patient's right atrium. After this placement, the atrial catheter 22 and the distal tu~e 20 are trimmed at the cervical incision and connected ~y the U-shaped connector 23, The introduction of the atrial catheter into the external jug-ular vein is again made possi~le owing to the relatively small diameter of the catheter, Leaving the tip of the catheter with in the right atrium inhibits ingrowth and eventual blockage of the catheter such as would occur if it were terminated near the 1 point at which it enters the venous system. The overall arrange-ment of the shunt system is illustrated in Fig. 2 in greater detail and the actual construction of the valve unit 19 is illustrated in Fig. 3.
In accordance with the concepts of the present inven-tion, the valving unit 19 comprises two pairs of one-way valves ~hich are connected in series through a flexible conduit. In the preferred embodiment illustrated, four identical one-way valve elements 31-34 are employed in a series-parallel arrange-ment in a flexible silicone rubber housing 35 i.e. valve element31 is in parallel with valve element 32 and this parallel pair is in series with a second parallel pair of elements 33 and 34.
The series connection is established by an elongate section 37 of the silastic rubber valve housing 35. This section 37 func-tions as a deformable conduit for purposes explained hereinafter.
Each of the valve elements 31-34 is generally of the type disclosed in U.S. Patent 3,288,142. This construction, illustrated in Fig. 4, employs a rigid base S1 in which is formed a conical valve seat 53 connected to an inlet port 55.
A rigid spherical valving element 57 is biased into the conical seat by a convoluted cantilever spring S9 which is secured to the base 51, e.g. by spot welding. A cylindrical shell 58 encloses the base 51, valving element 57 and spring 59 so as to facilitate its being held within the,overall valve assembly body 35. Another suitable form of valve element is that shown in U.S. patent number 4,332,255. In each case, the one way valv-ing is accomplished by a rigid or hard valving element (biased against a rigid seat). This is preferred over so~t valving elements e.g. such as those formed of silastic rubber, in that the hard surfacesare better suited for making a seal, even in , .~ .
., ~5;~4Q8 1 the presence of protein materials which might come to rest at the valving surface~ If complete closing is not o~tained some highly undesirable back flushing from the venous system may occur.
In addition to providing a larger total flow path the paralleling of valving elements is a greater protection against clogging since, even if one valving element s~ould clog, its parallel counterpart will typically ~e adeqùate to pass a ~enefi cial quantity of the ascitic fluid~
As noted previously, t~e valve assem~ is pre-fera~ly secured e,g, in a suitable subcutaneous pocket, at a point over the patient's sternum, With the valving element assembly 19 so located, it i8 possible for the patient himself or his physician to effect the actual pumping of fluid from the peritoneal cavity to the central venous system ~y manually press-ng against the valve assembly and there~y periodically collaps-ing or compressin~ the flexi~le conduit portion 37 ~etween the two pairs of paralleled valving elements. As will ~e understood, compressing this section will expell fluid through a downstream valvlng element, i,e., into the venous system, while releasing the manual pressure and allowing the conduit to assume its normal shape will draw fluid into the valving unit through the upstream valves i~e. the valving elements nearest the inlet tu~e in the peritoneal cavity~ The availability of this pumping procedure not only frees the patient from the tiresome exercises otherwise involYed in generating a negative pressure within the chest and a positive pressure in the peritoneal cavity. The valving elements and the small bore jugular catheter also can be effect-ively flushed by the pumping actions so that protein deposits w~ich might other~ise tend to clog the system can be effectively ~2408 1 cleared. In prior art systems where no such pumping action is available, it has ~een necessary to employ relatively large kore tu~ing for the venous catheter, This large size cannot--~e routed up to the external jugular as can the present system nor can it be then allowed to extend along the jugular internally to a lo-cation of such that the atrium ~here the danger of tissuing growth essentiaily absent. As indicated previously, it is highly advan-tageous to have the catheter enter the external jugular since it is much easier to accomplish insertion of the catheter at this point on the patient's neck.where this large vein is close to the surface, This easier access often means that the procedure can be performed under a local anesthesia rather than requiring the application of general anesthesia to a patient who may al-ready he considerably ~eakened ~y his illness~
The antecham~er 17, being similarly accessi~le near the surface of the patient, provide a means for momentarily back flushing the peritoneal catheter 13~ This is accomplished by just fully compressing the conduit portion 25 thereby éffectively ~locking flow through the valving elements and then compressing the antecham~er itself so as to generate a momentary back~low.
The antechAm~er also provides a convenient means for drawing off samples of ascitic fluid for analysis, For this purpose the antec~am~er is constructed of a flexi~le silicone ru~ber which tends to ~e self sealing with regard to needle punctures, The bottom of the antecham~er has a metal needle stopper, The fac~ that this system can ~e separated into its different components i.e~: peritoneal cathet~er 13, distal tube 20~ valve unit 19, atrial catheter 22, and connectors 12 and 23;
makes an~ surgical revision simple since there is no need to remove t~e ~hole system., hut only the failing part, B~ proper ~5- .

~2408 1 use of the antechamber and the valve pumping chamber, a failure along the system can be easily located.
In vie~ of the foregoing, it may ~e seen that several o~jects of the present invention are achieved and other advan-tageous results have ~een attained.
As various changes could ~e made in the above construc-tions uithout departing from the scope of the invention, it should ~e understood that allmatter contained in the a~ove description or shown in the accompan~ing drawings shall ~e interpreted as illustrative and not in a limiting means~

Claims (2)

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. Apparatus for treating a patient suffering from ascites, said apparatus comprising:
a perforate inlet catheter adapted to be implanted in the peritoneal cavity of the patient;
a drainage catheter adapted to be inserted into the patient's central venous system; and connecting said inlet catheter to said drainage catheter, a valve assembly comprising two pairs of one-way valves, the valves in each pair being in parallel with the pairs being connected in series through a flexible conduit, the conduit being deformable by manual pressure to effect pumping of ascitic fluid from the peritoneal cavity to the venous system.
2. Apparatus as set forth in claim 1 further comprising a flexible antechamber interposed between said inlet tube and said valve assembly, said antechamber being essentially self-sealing for hypodermic needle punctures.
CA000353261A 1979-06-08 1980-06-03 Method and apparatus for the treatment of ascites Expired CA1152408A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US046,947 1979-06-08
US06/046,947 US4261341A (en) 1979-06-08 1979-06-08 Method and apparatus for the treatment of ascites

Publications (1)

Publication Number Publication Date
CA1152408A true CA1152408A (en) 1983-08-23

Family

ID=21946238

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000353261A Expired CA1152408A (en) 1979-06-08 1980-06-03 Method and apparatus for the treatment of ascites

Country Status (7)

Country Link
US (1) US4261341A (en)
CA (1) CA1152408A (en)
DE (1) DE3020991A1 (en)
FR (1) FR2458287B1 (en)
GB (1) GB2055294A (en)
NL (1) NL8003261A (en)
SE (1) SE8004211L (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0091960A4 (en) * 1981-10-26 1985-07-30 Harry H Leveen Non-clogging valved drainage system for body fluids.
US4583967A (en) * 1984-02-13 1986-04-22 Cordis Corporation Telescoping catheter shunt system
US4657530A (en) * 1984-04-09 1987-04-14 Henry Buchwald Compression pump-catheter
EP0177250A3 (en) * 1984-10-01 1988-02-03 Cook Incorporated Implantable insulin administration device
FR2582222A1 (en) * 1985-05-21 1986-11-28 Applied Precision Ltd IMPLANTABLE MANUAL ACTION DEVICE FOR THE SEQUENTIAL DELIVERY OF DOSES OF A SUBSTANCE, ESPECIALLY THERAPEUTIC
US4681559A (en) * 1985-12-23 1987-07-21 Cordis Corporation Plural valve three stage pressure relief system
JPS63115538A (en) * 1986-11-04 1988-05-20 株式会社日本エム・デイ・エム Endocranial pressure measuring apparatus and ventricle shunt for measuring endocranial pressure
US4850955A (en) * 1986-12-02 1989-07-25 Codman & Shurtleff Body fluid transfer device
US4861331A (en) * 1988-03-24 1989-08-29 Pudenz-Schulte Medical Research Corp. Implantable shunt system and method of assembly
GB8824855D0 (en) * 1988-10-24 1988-11-30 Byrne P O Dialysis
DE4026202A1 (en) * 1990-08-18 1992-02-20 Andreas Dr Spiegelberg Hydrocephalus relief valve - has excessive cerebrospinal fluid passed via valve into pressure cylinder containing spring-loaded piston
US5830172A (en) * 1991-04-11 1998-11-03 Leveen; Harry H. Ascites valve
US5520632A (en) * 1991-04-11 1996-05-28 Robert Leveen Ascites valve
DE4307387C2 (en) * 1993-03-10 1995-04-06 Christoph Miethke Hydrocephalus valve
DE4401422B4 (en) * 1993-03-10 2004-02-05 Christoph Miethke Hydrocephalus valve with two valve openings
US6689085B1 (en) 1996-07-11 2004-02-10 Eunoe, Inc. Method and apparatus for treating adult-onset dementia of the Alzheimer's type
US5980480A (en) * 1996-07-11 1999-11-09 Cs Fluids, Inc. Method and apparatus for treating adult-onset dementia of the alzheimer's type
DE19645725C1 (en) * 1996-11-06 1997-12-11 Sican F & E Gmbh Sibet Implantable and controllable valve for medical use
US6022333A (en) * 1997-05-01 2000-02-08 S.L.I.M. Tech, Ltd. Method and system for removing materials from lymphatic and other fluids
US7189221B2 (en) * 1998-11-10 2007-03-13 Integra Life Sciences Corporation Methods for the treatment of a normal pressure hydrocephalus
US6875192B1 (en) 1998-11-10 2005-04-05 Eunoe, Inc. Devices and methods for removing cerebrospinal fluids from a patient's CSF space
GB2350794A (en) * 1999-04-20 2000-12-13 Nagy Adly Habib Implantable pump
ATE276786T1 (en) * 2000-12-11 2004-10-15 Christoph Miethke Gmbh & Co Kg HYDROCEPHAL VALVE
US7311690B2 (en) * 2002-02-25 2007-12-25 Novashunt Ag Implantable fluid management system for the removal of excess fluid
ES2428965T3 (en) * 2002-02-25 2013-11-12 Sequana Medical Ag Bladder bypass for excess fluid drainage
EP1428548B1 (en) * 2002-12-12 2008-11-05 Piolax Medical Devices, Inc. Catheter for use in peritoneovenous shunt
DE202004013704U1 (en) * 2004-07-16 2005-11-24 AVS Ing. J.C. Römer GmbH Non-return valve is mounted on Y-shaped leaf spring, bottom of Y forming mounting for attaching spring to valve casing and annular mounting for valve being mounted between its arms
US8202248B2 (en) 2004-08-18 2012-06-19 Sequana Medical Ag Dialysis implant and methods of use
US7559912B2 (en) * 2004-09-30 2009-07-14 Codman & Shurtleff, Inc. High pressure range hydrocephalus valve system
US20070219527A1 (en) * 2005-12-30 2007-09-20 Barron William R Catheter including a catheter valve, method of at least partially coating a catheter valve surface, and an apparatus for at least partially opening a catheter valve
CA2668077C (en) 2006-10-31 2015-12-29 Novashunt Ag An implantable fluid management device for the removal of excess fluid
DE102008030942A1 (en) 2008-07-02 2010-01-07 Christoph Miethke Gmbh & Co Kg Cerebrospinal fluid drainage
US20100217179A1 (en) * 2009-02-20 2010-08-26 Baxter International Inc. Bulk delivery peritoneal dialysis system and method
US9539081B2 (en) 2009-12-02 2017-01-10 Surefire Medical, Inc. Method of operating a microvalve protection device
US10052059B2 (en) * 2011-05-03 2018-08-21 Matthew J. Callaghan Apparatus and methods for accessing the lymphatic system
DE102010051743B4 (en) 2010-11-19 2022-09-01 C. Miethke Gmbh & Co. Kg Programmable hydrocephalus valve
CA3019557C (en) 2011-02-16 2020-07-21 Sequana Medical Ag Apparatus and methods for treating intracorporeal fluid accumulation
US8585635B2 (en) 2012-02-15 2013-11-19 Sequana Medical Ag Systems and methods for treating chronic liver failure based on peritoneal dialysis
US20140012180A1 (en) * 2012-05-01 2014-01-09 Nidus Medical, Llc Peritoneal drain and infusion
JP6461906B2 (en) 2013-03-15 2019-01-30 ハキム,カーロス・エー Externally programmable valve assembly
US9968740B2 (en) 2014-03-25 2018-05-15 Surefire Medical, Inc. Closed tip dynamic microvalve protection device
US20160287839A1 (en) 2015-03-31 2016-10-06 Surefire Medical, Inc. Apparatus and Method for Infusing an Immunotherapy Agent to a Solid Tumor for Treatment
JP7071338B2 (en) 2016-08-26 2022-05-18 セクアナ メディカル エヌブイ Systems and methods for managing and analyzing data generated by embedded devices
US10716922B2 (en) 2016-08-26 2020-07-21 Sequana Medical Nv Implantable fluid management system having clog resistant catheters, and methods of using same
US11400263B1 (en) 2016-09-19 2022-08-02 Trisalus Life Sciences, Inc. System and method for selective pressure-controlled therapeutic delivery
US10780250B1 (en) 2016-09-19 2020-09-22 Surefire Medical, Inc. System and method for selective pressure-controlled therapeutic delivery
US10588636B2 (en) 2017-03-20 2020-03-17 Surefire Medical, Inc. Dynamic reconfigurable microvalve protection device
AU2018273105B2 (en) 2017-05-24 2023-08-10 Sequana Medical Nv Direct sodium removal method, solution and apparatus to reduce fluid overload in heart failure patients
US11559618B2 (en) 2017-05-24 2023-01-24 Sequana Medical Nv Formulations and methods for direct sodium removal in patients having severe renal dysfunction
US11850398B2 (en) 2018-08-01 2023-12-26 Trisalus Life Sciences, Inc. Systems and methods for pressure-facilitated therapeutic agent delivery
US11338117B2 (en) 2018-10-08 2022-05-24 Trisalus Life Sciences, Inc. Implantable dual pathway therapeutic agent delivery port

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969066A (en) * 1956-10-02 1961-01-24 Holter Company Device for draining ventricular fluid in cases of hydrocephalus
US3020913A (en) * 1958-07-15 1962-02-13 William T Heyer Surgical drain
US3288142A (en) * 1964-04-27 1966-11-29 Hakim Salomon Hydrocephalus shunt with spring biased one-way valves
US3527226A (en) * 1966-02-03 1970-09-08 Cordis Corp Ventricular catheter with valve and pump flushing means
US3496878A (en) * 1967-04-07 1970-02-24 Bio Medical Systems Inc System and apparatus for transfer of human fluids
US3566868A (en) * 1968-08-26 1971-03-02 American Hospital Supply Corp Parenteral liquid administration set with injection site and method of making same
US3669094A (en) * 1970-07-06 1972-06-13 Heyer Schulte Corp Device and method for measuring intracranial pressure
US3910283A (en) * 1973-10-09 1975-10-07 Harry H Leveen Process for treatment of ascites and device to accomplish same

Also Published As

Publication number Publication date
SE8004211L (en) 1980-12-09
NL8003261A (en) 1980-12-10
DE3020991C2 (en) 1989-01-05
US4261341A (en) 1981-04-14
FR2458287A1 (en) 1981-01-02
FR2458287B1 (en) 1986-08-22
DE3020991A1 (en) 1980-12-18
GB2055294A (en) 1981-03-04

Similar Documents

Publication Publication Date Title
CA1152408A (en) Method and apparatus for the treatment of ascites
US20230043946A1 (en) Arteriovenous graft for hemodialysis with puncture-resistant posterior and side walls
DE69938145T2 (en) SMOOTH VESSEL FOR CHAMBER SUPPORT DEVICE
US5807356A (en) Catheter with valve
US4578057A (en) Ventricular right angle connector and system
US7824358B2 (en) Heart pump connector
US6398764B1 (en) Subcutaneously implanted cannula and method for arterial access
US4240434A (en) Peritoneo-venous shunt
US4086665A (en) Artificial blood conduit
JP2879097B2 (en) Artificial dialysis machine
US4118806A (en) Prosthetic blood vessel
US7837646B2 (en) Hydrocephalus shunt system quick connector assembly
US4795437A (en) Siphon control device
US20020095116A1 (en) Apparatus and method for replacing aortic valve
CN103209732B (en) Implanted access interface
JPH11500031A (en) Hemodialysis access device
US20140012180A1 (en) Peritoneal drain and infusion
DE69831479D1 (en) DEVICE FOR PRODUCING A REPLACEMENT SOLUTION
US20080172002A1 (en) Flexible valve for blood treatment set
JPH04507050A (en) Vascular access system for extracorporeal processing of blood
US20110172692A1 (en) Hemodialysis arterio-venous graft with a ring-like diameter-adjustable device
USRE49658E1 (en) Intercostal pump
JP2006142032A (en) Ventriculostomy reservoir
GB2105197A (en) Body implantable connector for connection to an implant device
US9861734B2 (en) Bifurcated peritoneal catheter

Legal Events

Date Code Title Description
MKEX Expiry