CA1067469A - Disposable tubing harness for use with blood washing apparatus - Google Patents
Disposable tubing harness for use with blood washing apparatusInfo
- Publication number
- CA1067469A CA1067469A CA288,973A CA288973A CA1067469A CA 1067469 A CA1067469 A CA 1067469A CA 288973 A CA288973 A CA 288973A CA 1067469 A CA1067469 A CA 1067469A
- Authority
- CA
- Canada
- Prior art keywords
- array
- packages
- blood
- board
- adjacent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3692—Washing or rinsing blood or blood constituents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/6851—With casing, support, protector or static constructional installations
Abstract
DISPOSABLE TUBING HARNESS FOR
USE WITH BLOOD WASHING APPARATUS
Abstract of the Disclosure Disposable flexible tubing harness for use with a blood washing device providing connections between packages for containing liquids and the blood washing device.
S P E C I F I C A T I O N
USE WITH BLOOD WASHING APPARATUS
Abstract of the Disclosure Disposable flexible tubing harness for use with a blood washing device providing connections between packages for containing liquids and the blood washing device.
S P E C I F I C A T I O N
Description
~:0674G9 The present invention relatas to blood washing apparatus and more particularly to a disposable tubing ar-rangement or harness for use with a blood washing apparatus.
B}ood washing is a procedure;known to the art, for example, as described~in U.S. Pa~ent 3,982,691 - Centrifuge SeparatLon a~d Washing Devlce and Method - Charles A. Schutz ssued September 28, 1976. As described in~the above-noted : , UnLted States patent human blood from volunteer donors Ls washed to~remove unwarted constL~tuents such~as contaminants, toxicants, viruses, medLcants, glycerLnes,~cellular debris ~
and the lLke, using a devLce~based on centrLfugal separation.
Such a device includes a rotatabLe enclosure into whLch lLquids, such~as bLood and wasll LLquids, e.g.,;~saline solutions are mJected, and~from whLch the~washed~blood, wash LLquids and urwanted~constLtuents are removed. While ; ehe device descrLbed~in the above-noted~patent can be used~ ~
to wash blood continuously, in-a particular mode~of operation, a predetermined amount of blood e.g.~, a package avaLlable ~ rom a blood b~anking organLzatLon, Ls washed using pre--~ ~ 20 determined packaged quantities of wash soLution. Under such~
:
circumstances it IS desirabLe~to provLde a disposable con-nection between the~packages~ of blood and wash liquids and the blood washing device, and between the blood washLng de-ViC2 and liquLd collection packages.
It is therefore an object of the present invention to provide a disposable tubing harness connection between a '` ~:
:
f~
i7469 blood washing device and packaged liquids and liquid collection packages.
Other objects will be apparent from the following description and claims taken in conjunction with the drawing wherein ~ ~
Figure 1 shows somewhat schematically a blood washing device which is provided with a disposable tubing harness arrangement in accordance with th~ present invention, Figures 2, 2(a) and 2(b) show in more detail thc disposable tubing harness arrangement in accordance with the present invention, . Figure 3 is a section through 3-3 of Figure 2 Figure 4~shows the harness support member of Figure~2 without tubing and Figure 5 show6 a technique for connecting liquid containing packages to the tubes of the harness arrangement of the present invention.
With reference to Figure 1 of the drawing, a blood washing apparatus is indicated at l having an ;; enclosing hous~ing 3 in which is containe~ a rotatable enclosure means 5 such as the type described in the above-noted U.S. patent 3,982,691 which washes~blood cells in the manner described in the patent.
A fluid connector 7, supported on arm 4 above entry conduit 8 and exit conduit 10 provides fluid co~munication with blood washing enclosure means 5.
~I.uid connector 7 has two conduits 9 and 11 for the _ 3 _ ~067~69 entry and removal of liquid as hereinaftex described, Housing member 3 is provided with a shel member 13 and side supports 14 and 8 which supports a container 15, having partitions 18, e.g. made of card-~board, which supportably holds an initially empty wastepackage 17, a low concentration ~aline solut~ion containing package 19~, and a high concentration saline solution conta~ning package 2L~. A blood containing package 23, .
such as a package obtained from a blood bank, is supported by means of hooks on~ side support 14 as indiaated at 25.
A washed bload collectlon package 27, initialLy arran8ed in~container lS,;is~simiLarly supported on side ;~ support 8 durlng blood washing. The above-described~
packages~L7, L9, 21,~23;and 27~ are suitably made of a ~
transparent fLexibLe pLastic màterial such qs~poLyolefins and the like. ~
The horizontally disposed array of adjacent ; ~ packages 17, 19, 21, 23 and 27 are located above a board-Like member 29 which is removably engaged to ~ ;
housing 3 by support pins as ,ndicated at 31. Board-like member 29 is~suitably made of polyvinyl chloride and contains grooves 33, 33~' ~ etG., as particulæLy indicated in Figure 2 and 4 which respectively engage and secureLy hoLd flexible tubes 35, 35', etc., which are transparent and also suitably made of polyvinyL and the Like. Board .
~ - 4 -~\
~)67~;9 like member 29 also has openings a~ hereinater described to provide clearance for valves ancl sensors which are mounted on housing 3 and which receive electrical sig~als from or provide electrical signals to a conventional elec-trical control unit 43 whic~ is contained within housing 3. Housing 3 also contains conventional peristaltic pumps 45 and 47 which have motor driven shaft extensions 49 and 51 respectively which have cross-sections lying in substantially the same vertical plane as the grooves 33, 33', etc., of board-like member 29. The rotation o~
the shafts 49 and 51 of pumps 45 and 47 may be controlled : by signals from control unit 43.
With reference to Figures 2, 3 and 4 packages 17, l9, 21, 23 and 27 are connected to flexibLe tubes 35-35'7", for example by means of a "Spike" connector arrangement as shown in Figure 5 comprising a pointed extension member 22 which is force fitted by hand in conduit extension 26 and pierces a plastic membrane 30.
Board-like member 29 is mo~nted on pin arrangement 31 on housing 3 by means of holes 53 in board-like member 29. Each of the flexible conduits 35-35"" is force fitted into a groove 33-33"" which extends from the upper edge S5 of board-like member 29 to the side 57 of board-like member 29 which is adjacent the horizontally disposed peristaltî.c pump shafts 49 and 51 as shown in Figure 1. An aclditional groove 36 extends from side 57 into the interior of '469 ```
board-like ~ember 29 to join with groove 33' at 38 into ~: a single groove 40. A further additional groove 39 extends parallelto groove 36 and joins groove 36 at 94.~
As shown in Figure 2, grooves 33 and 33" join at 59 into a single groove 61~. Bo æd-like member~29 is provided with openings at~locations along various groo~e paths to accommodate optical~s~ensors 63 and 65, in opening~: ~
37, and pinch valves 71,~73, 75, 77, 79 and 91 in openings 70, 72,:74, 76, 78 and 90 respectively. The abova noted optical sensors and;pinch valves are mounted on housing 3 and are electrically connected to control unit 43 as shown in Flgure 1.
With the flexibLe tubes;35-35"";a3sembled in :
board-like`:member 29 and::the tubes connec~ted to packages:
: 17, 19, 21,23~and 27~as shown in Figure~l, loops 8:1~and 83 h ; : :` ~are fitted around peris:taltic:pumps shafts 49 and 51 as also shown in Figure 1 and held flxed with respect to the :: :
shafts by clamps 85 and 87 as shown in Figure:l.
: With the tube harness arran8ement of the present~
- invention in:piace as described above,~the blood washing apparatus shown in Figure l~can:be opéra~ed.~ For example?
low concentration saline s;olution from package l9 is pumped~
b~ the rotation of peristaltic pump shaft 49 through tube :: :
35" to T connection 59, valve 91 being open, to T connection 93 where flow is reversed, due to valve 77 being closed and valve 75 being open, whereby low concentration saline ~10~7469 solution passes through tube section 95 via connector 7 into rotating anclosure member 5, thereby priming enclosure member 5. Low saline solution in excess of th~t required for priming exits enclosure~member S via connector 7 and tube section 97 through T connection~99 and tube 35' to waste package 17. After priming~with low concentration saline solution valve 73 is opened and, blood from packags 23 is pumped via tube 35 into~enclosure member S by the same path as the previously described~low concentration saline solution prime. Optical sensor 65 detects the start and finish of blood flow through transparent tube 35 and at the~finish provide an electrical signal to eontrol unit~43, shown~in Figure l, so that~signals~;can be provided~to the valves and pumps in the foLlowing "wash"~
step. ; ~
; In the~"wash"~step, pump s~a~:ts~49 and 51 can be both operated to provide a continuous flow of saline :
solution ~ predetermined relatively high concentration into enclosure member 5, the~higher saline concentration ~20 solution proceeding directly from package 21 via flexible tube 35"" through T connection 101 and connector 7 to :: :: : :
enclosure member 5; the low concsntration sali~e solution proceeds from package 19 in the same manner as~the above :
; ~ described priming step. During the washing step, saline solution containing contsminants , etc., i.s, waste liquid 7~69 is continuously removed from enclosure member 5 to waste package 17 in the same manner as excess saLine solution was removed in the above described priming step. When the predetermLned washing period is over, the washed blood is collected from enclosure member 5 into package 27 by centrifugal force and the action of pump shaft 49 which pumps low:concentration salLne solution from package 19 into enclosure member 5 by :: : :
: ; way of tube 35", open valve 91 T connection 59, tubes 8L
: 10 and 36~ T connection 93, open valve 77, T connection 99 and tube 97. The washed blood exits through T connection 101 tube 105, open valve 71 and tube 35 "' to blood collection pac~age 27. During the~oregoing collection step valves 79 and 75:are c:losed and pump 50 lS deactua~ed.
The passage of washed blood~is detected by optical sensor 107 and when blood is no longer detected the pump shaft ~ 49 is stopped by a signal from control unit 43. Optical : ~ :
sensor 63 monitors the flow of waste liquid into waste collection package 17.
:
:
B}ood washing is a procedure;known to the art, for example, as described~in U.S. Pa~ent 3,982,691 - Centrifuge SeparatLon a~d Washing Devlce and Method - Charles A. Schutz ssued September 28, 1976. As described in~the above-noted : , UnLted States patent human blood from volunteer donors Ls washed to~remove unwarted constL~tuents such~as contaminants, toxicants, viruses, medLcants, glycerLnes,~cellular debris ~
and the lLke, using a devLce~based on centrLfugal separation.
Such a device includes a rotatabLe enclosure into whLch lLquids, such~as bLood and wasll LLquids, e.g.,;~saline solutions are mJected, and~from whLch the~washed~blood, wash LLquids and urwanted~constLtuents are removed. While ; ehe device descrLbed~in the above-noted~patent can be used~ ~
to wash blood continuously, in-a particular mode~of operation, a predetermined amount of blood e.g.~, a package avaLlable ~ rom a blood b~anking organLzatLon, Ls washed using pre--~ ~ 20 determined packaged quantities of wash soLution. Under such~
:
circumstances it IS desirabLe~to provLde a disposable con-nection between the~packages~ of blood and wash liquids and the blood washing device, and between the blood washLng de-ViC2 and liquLd collection packages.
It is therefore an object of the present invention to provide a disposable tubing harness connection between a '` ~:
:
f~
i7469 blood washing device and packaged liquids and liquid collection packages.
Other objects will be apparent from the following description and claims taken in conjunction with the drawing wherein ~ ~
Figure 1 shows somewhat schematically a blood washing device which is provided with a disposable tubing harness arrangement in accordance with th~ present invention, Figures 2, 2(a) and 2(b) show in more detail thc disposable tubing harness arrangement in accordance with the present invention, . Figure 3 is a section through 3-3 of Figure 2 Figure 4~shows the harness support member of Figure~2 without tubing and Figure 5 show6 a technique for connecting liquid containing packages to the tubes of the harness arrangement of the present invention.
With reference to Figure 1 of the drawing, a blood washing apparatus is indicated at l having an ;; enclosing hous~ing 3 in which is containe~ a rotatable enclosure means 5 such as the type described in the above-noted U.S. patent 3,982,691 which washes~blood cells in the manner described in the patent.
A fluid connector 7, supported on arm 4 above entry conduit 8 and exit conduit 10 provides fluid co~munication with blood washing enclosure means 5.
~I.uid connector 7 has two conduits 9 and 11 for the _ 3 _ ~067~69 entry and removal of liquid as hereinaftex described, Housing member 3 is provided with a shel member 13 and side supports 14 and 8 which supports a container 15, having partitions 18, e.g. made of card-~board, which supportably holds an initially empty wastepackage 17, a low concentration ~aline solut~ion containing package 19~, and a high concentration saline solution conta~ning package 2L~. A blood containing package 23, .
such as a package obtained from a blood bank, is supported by means of hooks on~ side support 14 as indiaated at 25.
A washed bload collectlon package 27, initialLy arran8ed in~container lS,;is~simiLarly supported on side ;~ support 8 durlng blood washing. The above-described~
packages~L7, L9, 21,~23;and 27~ are suitably made of a ~
transparent fLexibLe pLastic màterial such qs~poLyolefins and the like. ~
The horizontally disposed array of adjacent ; ~ packages 17, 19, 21, 23 and 27 are located above a board-Like member 29 which is removably engaged to ~ ;
housing 3 by support pins as ,ndicated at 31. Board-like member 29 is~suitably made of polyvinyl chloride and contains grooves 33, 33~' ~ etG., as particulæLy indicated in Figure 2 and 4 which respectively engage and secureLy hoLd flexible tubes 35, 35', etc., which are transparent and also suitably made of polyvinyL and the Like. Board .
~ - 4 -~\
~)67~;9 like member 29 also has openings a~ hereinater described to provide clearance for valves ancl sensors which are mounted on housing 3 and which receive electrical sig~als from or provide electrical signals to a conventional elec-trical control unit 43 whic~ is contained within housing 3. Housing 3 also contains conventional peristaltic pumps 45 and 47 which have motor driven shaft extensions 49 and 51 respectively which have cross-sections lying in substantially the same vertical plane as the grooves 33, 33', etc., of board-like member 29. The rotation o~
the shafts 49 and 51 of pumps 45 and 47 may be controlled : by signals from control unit 43.
With reference to Figures 2, 3 and 4 packages 17, l9, 21, 23 and 27 are connected to flexibLe tubes 35-35'7", for example by means of a "Spike" connector arrangement as shown in Figure 5 comprising a pointed extension member 22 which is force fitted by hand in conduit extension 26 and pierces a plastic membrane 30.
Board-like member 29 is mo~nted on pin arrangement 31 on housing 3 by means of holes 53 in board-like member 29. Each of the flexible conduits 35-35"" is force fitted into a groove 33-33"" which extends from the upper edge S5 of board-like member 29 to the side 57 of board-like member 29 which is adjacent the horizontally disposed peristaltî.c pump shafts 49 and 51 as shown in Figure 1. An aclditional groove 36 extends from side 57 into the interior of '469 ```
board-like ~ember 29 to join with groove 33' at 38 into ~: a single groove 40. A further additional groove 39 extends parallelto groove 36 and joins groove 36 at 94.~
As shown in Figure 2, grooves 33 and 33" join at 59 into a single groove 61~. Bo æd-like member~29 is provided with openings at~locations along various groo~e paths to accommodate optical~s~ensors 63 and 65, in opening~: ~
37, and pinch valves 71,~73, 75, 77, 79 and 91 in openings 70, 72,:74, 76, 78 and 90 respectively. The abova noted optical sensors and;pinch valves are mounted on housing 3 and are electrically connected to control unit 43 as shown in Flgure 1.
With the flexibLe tubes;35-35"";a3sembled in :
board-like`:member 29 and::the tubes connec~ted to packages:
: 17, 19, 21,23~and 27~as shown in Figure~l, loops 8:1~and 83 h ; : :` ~are fitted around peris:taltic:pumps shafts 49 and 51 as also shown in Figure 1 and held flxed with respect to the :: :
shafts by clamps 85 and 87 as shown in Figure:l.
: With the tube harness arran8ement of the present~
- invention in:piace as described above,~the blood washing apparatus shown in Figure l~can:be opéra~ed.~ For example?
low concentration saline s;olution from package l9 is pumped~
b~ the rotation of peristaltic pump shaft 49 through tube :: :
35" to T connection 59, valve 91 being open, to T connection 93 where flow is reversed, due to valve 77 being closed and valve 75 being open, whereby low concentration saline ~10~7469 solution passes through tube section 95 via connector 7 into rotating anclosure member 5, thereby priming enclosure member 5. Low saline solution in excess of th~t required for priming exits enclosure~member S via connector 7 and tube section 97 through T connection~99 and tube 35' to waste package 17. After priming~with low concentration saline solution valve 73 is opened and, blood from packags 23 is pumped via tube 35 into~enclosure member S by the same path as the previously described~low concentration saline solution prime. Optical sensor 65 detects the start and finish of blood flow through transparent tube 35 and at the~finish provide an electrical signal to eontrol unit~43, shown~in Figure l, so that~signals~;can be provided~to the valves and pumps in the foLlowing "wash"~
step. ; ~
; In the~"wash"~step, pump s~a~:ts~49 and 51 can be both operated to provide a continuous flow of saline :
solution ~ predetermined relatively high concentration into enclosure member 5, the~higher saline concentration ~20 solution proceeding directly from package 21 via flexible tube 35"" through T connection 101 and connector 7 to :: :: : :
enclosure member 5; the low concsntration sali~e solution proceeds from package 19 in the same manner as~the above :
; ~ described priming step. During the washing step, saline solution containing contsminants , etc., i.s, waste liquid 7~69 is continuously removed from enclosure member 5 to waste package 17 in the same manner as excess saLine solution was removed in the above described priming step. When the predetermLned washing period is over, the washed blood is collected from enclosure member 5 into package 27 by centrifugal force and the action of pump shaft 49 which pumps low:concentration salLne solution from package 19 into enclosure member 5 by :: : :
: ; way of tube 35", open valve 91 T connection 59, tubes 8L
: 10 and 36~ T connection 93, open valve 77, T connection 99 and tube 97. The washed blood exits through T connection 101 tube 105, open valve 71 and tube 35 "' to blood collection pac~age 27. During the~oregoing collection step valves 79 and 75:are c:losed and pump 50 lS deactua~ed.
The passage of washed blood~is detected by optical sensor 107 and when blood is no longer detected the pump shaft ~ 49 is stopped by a signal from control unit 43. Optical : ~ :
sensor 63 monitors the flow of waste liquid into waste collection package 17.
:
:
Claims (2)
1. In combination with a blood washing apparatus having a (i) a housing member supporting a horizontal array of packages adapted to contain blood, saline solution and blood washing waste liquid (ii) a pair of adjacent peristaltic pump shafts Located below and to the side of said array of packages (iii) a rotatable enclosure member arranged below said array of packages adapted to receive blood and saline solution from selected packages of said array and adapted to provide washed blood and waste liquid for transmission to selected packages of said array, a tubing harness arrangement for providing fluid paths between the packages of said array and said rotatable enclosure comprising (a) a board-like member removably vertically mounted on said housing member below said array of packages and adjacent said pair of peristaltic pump shafts in a common plane with a cross-section of said shafts, said board-like member having a plurality grooves extending from its upper horizontal side adjacent said array of package to a vertical side adjacent said pair of peristaltic pump shafts and an additional groove extending from said vertical side to a selected one of said plurality of grooves, a plurality of flexible tube members engaged in said grooves and adapted to be respectively connected to a selected package of said array adjacent the upper side of said board-like member and adapted to provide fluid paths from said array of packages to said rotatable enclosure member, two of said plurality of flexible tube members being formed in a loop adjacent said vertical side of said board-like member which are respectively engaged to a said peristaltic pump shaft, the flexible tube member of one of said loops being doubled back to engage in said additional groove in said board-like member to firmly engage said board-like member to said peristaltic pump shaft.
2, A combination in accordance with claim 1 wherein said flexible tubes are transparent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/737,607 US4069968A (en) | 1976-11-01 | 1976-11-01 | Disposable tubing harness for use with blood washing apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1067469A true CA1067469A (en) | 1979-12-04 |
Family
ID=24964552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA288,973A Expired CA1067469A (en) | 1976-11-01 | 1977-10-18 | Disposable tubing harness for use with blood washing apparatus |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4069968A (en) |
| JP (1) | JPS5356892A (en) |
| BE (1) | BE860372A (en) |
| BR (1) | BR7707259A (en) |
| CA (1) | CA1067469A (en) |
| DE (1) | DE2748379A1 (en) |
| DK (1) | DK483577A (en) |
| FR (1) | FR2368965A1 (en) |
| NL (1) | NL7711955A (en) |
| SE (1) | SE7712289L (en) |
| ZA (1) | ZA776462B (en) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5006103A (en) * | 1977-08-12 | 1991-04-09 | Baxter International Inc. | Disposable container for a centrifuge |
| US5217427A (en) * | 1977-08-12 | 1993-06-08 | Baxter International Inc. | Centrifuge assembly |
| US5217426A (en) * | 1977-08-12 | 1993-06-08 | Baxter International Inc. | Combination disposable plastic blood receiving container and blood component centrifuge |
| US5571068A (en) * | 1977-08-12 | 1996-11-05 | Baxter International Inc. | Centrifuge assembly |
| US4379452A (en) * | 1977-10-18 | 1983-04-12 | Baxter Travenol Laboratories, Inc. | Prepackaged, self-contained fluid circuit module |
| US4136818A (en) * | 1977-10-25 | 1979-01-30 | Union Carbide Corporation | Light-shielding tube holder for use with blood washing apparatus |
| DE2749367A1 (en) * | 1977-11-04 | 1979-05-10 | Peter R Dr Med Lorenz | PLIERS HOLDER FOR THE FILLING DEVICE FOR ZONAL ROTORS |
| JPS61113461A (en) * | 1984-11-06 | 1986-05-31 | 鐘淵化学工業株式会社 | Circuit body for treating blood component |
| WO1989001792A1 (en) * | 1987-08-28 | 1989-03-09 | Haemonetics Corporation | Method and apparatus for cell washing |
| US4936820A (en) * | 1988-10-07 | 1990-06-26 | Baxter International Inc. | High volume centrifugal fluid processing system and method for cultured cell suspensions and the like |
| US5078671A (en) * | 1988-10-07 | 1992-01-07 | Baxter International Inc. | Centrifugal fluid processing system and method |
| US5441636A (en) * | 1993-02-12 | 1995-08-15 | Cobe Laboratories, Inc. | Integrated blood treatment fluid module |
| US5460493A (en) * | 1993-11-17 | 1995-10-24 | Baxter International Inc. | Organizer frame for holding an array of flexible tubing in alignment with one or more peristaltic pump rotors |
| WO1995017260A1 (en) * | 1993-12-22 | 1995-06-29 | Baxter International Inc. | Centrifuge with sloped rotational axis and sloped control panel |
| US5551942A (en) * | 1993-12-22 | 1996-09-03 | Baxter International Inc. | Centrifuge with pivot-out, easy-load processing chamber |
| US5482440A (en) * | 1993-12-22 | 1996-01-09 | Baxter Int | Blood processing systems using a peristaltic pump module with valve and sensing station for operating a peristaltic pump tube cassette |
| US5484239A (en) * | 1993-12-22 | 1996-01-16 | Baxter International Inc. | Peristaltic pump and valve assembly for fluid processing systems |
| CA2155735A1 (en) * | 1993-12-22 | 1995-06-29 | Richard C. Giesler | Self-priming drip chamber with enhanced visibility |
| US5746708A (en) * | 1993-12-22 | 1998-05-05 | Baxter International Inc. | Peristaltic pump tube holder with pump tube shield and cover |
| US5870805A (en) * | 1997-01-06 | 1999-02-16 | Baxter International Inc. | Disposable tubing set and organizer frame for holding flexible tubing |
| US6589482B1 (en) | 1997-02-14 | 2003-07-08 | Nxstage Medical, Inc. | Extracorporeal circuits for performing hemofiltration employing pressure sensing without an air interface |
| US6638478B1 (en) | 1997-02-14 | 2003-10-28 | Nxstage Medical, Inc. | Synchronized volumetric fluid balancing systems and methods |
| US6830553B1 (en) | 1997-02-14 | 2004-12-14 | Nxstage Medical, Inc. | Blood treatment systems and methods that maintain sterile extracorporeal processing conditions |
| US6852090B2 (en) * | 1997-02-14 | 2005-02-08 | Nxstage Medical, Inc. | Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge |
| US6595943B1 (en) | 1997-02-14 | 2003-07-22 | Nxstage Medical, Inc. | Systems and methods for controlling blood flow and waste fluid removal during hemofiltration |
| US6554789B1 (en) | 1997-02-14 | 2003-04-29 | Nxstage Medical, Inc. | Layered fluid circuit assemblies and methods for making them |
| US20040243047A1 (en) * | 1997-02-14 | 2004-12-02 | Brugger James M. | Single step fluid circuit engagement device and method |
| AU3273101A (en) * | 1997-02-14 | 2001-06-04 | Nxstage Medical, Inc. | Extracorporeal circuits for performing hemofiltration employing pressure sensingwithout an air interface |
| US6673314B1 (en) | 1997-02-14 | 2004-01-06 | Nxstage Medical, Inc. | Interactive systems and methods for supporting hemofiltration therapies |
| US6638477B1 (en) | 1997-02-14 | 2003-10-28 | Nxstage Medical, Inc. | Fluid replacement systems and methods for use in hemofiltration |
| US6196503B1 (en) * | 1997-07-17 | 2001-03-06 | Constance M. Cernosek | Cable-tubing organizer system for medical care environments |
| US6008009A (en) * | 1998-04-17 | 1999-12-28 | Universities Space Research Association | Centrifuge-operated specimen staining method and apparatus |
| US7780619B2 (en) * | 1999-11-29 | 2010-08-24 | Nxstage Medical, Inc. | Blood treatment apparatus |
| IT1318444B1 (en) * | 2000-04-03 | 2003-08-25 | Dideco Spa | INTRAOPERATIVE SELF-TRANSFUSION DEVICE. |
| ITMI20031715A1 (en) * | 2003-09-05 | 2005-03-06 | Dideco Spa | CONTROL DEVICE IN THE DIFFERENTIATED COLLECTION OF THE |
| US7060018B2 (en) * | 2003-09-11 | 2006-06-13 | Cobe Cardiovascular, Inc. | Centrifuge apparatus for processing blood |
| ITMI20032341A1 (en) * | 2003-11-28 | 2005-05-29 | Dideco Spa | AUTOTRASFUSION DEVICE WITH UNIFICATION OF PROCEDURES TO BE CARRIED OUT ON THE PATIENT. |
| EP1950568B1 (en) * | 2005-10-05 | 2017-08-09 | Nikkiso Company Limited | Biological component measuring unit |
| DE102008026916A1 (en) * | 2008-06-05 | 2009-12-17 | Fresenius Medical Care Deutschland Gmbh | Organizer for releasably receiving components of blood tubing sets and methods of making and preparing same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452924A (en) * | 1965-02-03 | 1969-07-01 | Sorvall Inc Ivan | System and method for washing blood and the like |
| US3489145A (en) * | 1966-08-08 | 1970-01-13 | Surgeon General Of The Public | Method and apparatus for continuous separation of blood in vivo |
| US3634228A (en) * | 1969-10-22 | 1972-01-11 | Cryogenic Technology Inc | Sterile washing method and apparatus |
| US3877634A (en) * | 1973-05-25 | 1975-04-15 | Du Pont | Cell washing centrifuge apparatus and system |
| JPS50107565A (en) * | 1974-01-29 | 1975-08-25 |
-
1976
- 1976-11-01 US US05/737,607 patent/US4069968A/en not_active Expired - Lifetime
-
1977
- 1977-10-18 CA CA288,973A patent/CA1067469A/en not_active Expired
- 1977-10-28 FR FR7732565A patent/FR2368965A1/en not_active Withdrawn
- 1977-10-28 DE DE19772748379 patent/DE2748379A1/en active Pending
- 1977-10-31 ZA ZA00776462A patent/ZA776462B/en unknown
- 1977-10-31 SE SE7712289A patent/SE7712289L/en unknown
- 1977-10-31 NL NL7711955A patent/NL7711955A/en not_active Application Discontinuation
- 1977-10-31 BR BR7707259A patent/BR7707259A/en unknown
- 1977-10-31 DK DK483577A patent/DK483577A/en unknown
- 1977-10-31 BE BE182262A patent/BE860372A/en unknown
- 1977-10-31 JP JP12979877A patent/JPS5356892A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL7711955A (en) | 1978-05-03 |
| DE2748379A1 (en) | 1978-05-03 |
| BR7707259A (en) | 1978-07-11 |
| JPS5356892A (en) | 1978-05-23 |
| ZA776462B (en) | 1978-08-30 |
| FR2368965A1 (en) | 1978-05-26 |
| SE7712289L (en) | 1978-05-01 |
| BE860372A (en) | 1978-05-02 |
| US4069968A (en) | 1978-01-24 |
| DK483577A (en) | 1978-05-02 |
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