The bovine coccygeal disc provides such samples, with similar properties in terms of composition, swelling pressure and metabolism to those seen in human discs [4]. We have shown in this study that breakdown and loss of GAGs can be induced, sufficient to inject a potential nuclear replacement for subsequent testing.
Feb 25, 2008
May 6, 2021 · We sought to deconvolute the cell composition of the nucleus pulposus (NP) and the annulus fibrosus (AF) of bovine intervertebral discs.
Bovine coccygeal discs were maintained for up to 1 week in a simple culture system that allows for compressive loading of the intervertebral disc. Cell ...
It is composed of a network of collagen fibrils and hydrated proteoglycan molecules. Vascularized by microscopic vessels during development, they disappear once ...
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To investigate the biomechanical effects of injections of a protease on the characteristics of bovine coccygeal and human lumbar disc motion segments.
INTRODUCTION. Aging and degeneration affect the turnover of the proteoglycans and collagens that make up most of the extracellular matrix of.
Jun 8, 2024 · Bovine coccygeal intervertebral discs contain multipotent Tie2+ cells which can differentiate into osteogenic and adipogenic lineages.
Coccygeal discs are a readily obtainable and cheap source of disc material, and they are easy to dissect out. Since the general properties of these discs are ...
Bovine coccygeal discs have been suggested as a suitable alternative model because they are readily available, in contrast to human discs, and represent a ...
... disc level, age, and tissue region. To determine whether bovine coccygeal discs are a suitable model to study human lumbar discs. Bovine coccygeal discs ...