Roche Holding AG (Roche) is a research-based healthcare company. The Company's operating businesses are organized into two divisions: Pharmaceuticals and Diagnostics. The Company's Pharmaceuticals Division comprises the two business segments: Roche Pharmaceuticals and Chugai. The Diagnostics Division consists of four business areas: Diabetes Care, Molecular Diagnostics, Professional Diagnostics and Tissue Diagnostics. Its activities are structured into six geographical segments: North America; Asia-Pacific; Western Europe; Latin America; Europe, the Middle East and Africa (EMEA), and Japan. The Company focuses on a select group of disease areas, including oncology, hematology, neuroscience, immunology, inflammation, ophthalmology, infectious and rare diseases. Its key pharmaceutical products include Avastin, Herceptin, Perjeta, Kadcyla, MabThera/Rituxan, Lucentis, Actemra/RoActemra, Zelboraf and Gazyva/Gazyvaro.