Instem plc, formerly Instem Life Science Systems plc, is a provider of information technology (IT) applications to the global early development healthcare market. It is focused on the early development sector of the drug and chemical research and development industry, from late discovery and lead optimization through to the Phase I clinical evaluation stage. Its products include Provantis, Provantis Small Lab Solutions and Centrus. Provantis is n integrated software system for both single users and global organizations engaged in early development safety assessment (EDSA) evaluation studies, such as universities, commercial organisations and government research institutes. The Provantis provides solutions to General toxicology, Pathology, Clinical pathology and Tables and statistics. In May 2013, Instem PLC announced the acquisition of Logos Holdings Limited along with its subsidiaries Logos EDC Solutions Limited and Logos Technologies Inc.