Nuvo Pharmaceuticals Inc., formerly Nuvo Research Inc., is a Canada-based healthcare company. The Company offers a range of commercial products, including Pennsaid 2%, Pennsaid and the heated lidocaine/tetracaine (HLT) patch. The Company's Pennsaid 2% is a non-steroidal anti-inflammatory drug (NSAID) containing 2% diclofenac sodium. Its Pennsaid 2% is indicated for treating the pain of osteoarthritis (OA) of the knee and also acute strains and sprains. The Company's Pennsaid is a topical pain product, which is used to treat the signs and symptoms of OA of the knee. The Pennsaid combines the transdermal carrier with diclofenac sodium, which is a NSAID and delivers the active drug through the skin at the site of pain. Its HLT Patch is a topical patch that combines lidocaine, tetracaine and heat, using Controlled Heat-Assisted Drug Delivery (CHADD) technology. HLT Patch provides local analgesia prior to painful needle procedures, such as dialysis, blood draws and pediatric needles.