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TRM6/61 connects PKCα with translational control through tRNA i Met ...
Accordingly, in mammalian C6 cells, small interfering RNA (siRNA)-mediated depletion of either TRM6 or TRM61, or both (Figure 2a) decreased significantly cell growth (Figure 2b) and caused up to 50% of cell death following 72 h as visualized by annexin ...
Hedgehog signaling activation induces stem cell proliferation and hormone ...
Scale bar in (a–c) 20 μm; Scale bar in (d–f) 50 μm. .... For in vitro studies 5 μM cyclopamine (Toronto Research Chemicals Inc.) dissolved in ethanol (EtOH), 10 μM tamoxifen in DMSO and 1 μg/ml recombinant murine Shh-N (rShh-N; R&D systems) in HD ...
LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung ...
Tissue sections (5 μm) were stained with anti-LZTFL1 antibody and assigned expression scores—staining intensity (0, no staining; 1, weak; 2, medium; 3 strong) multiplied by the proportion of stained cells (1, <50% stained; 2, >50%stained) as described ...
Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via ...
Concentrations of vector genome in the blood were below the limit of quantitation (50 vg/�g genomic DNA) at 4 hours or 24 hours post-vector injection in all the control and low-dose vector animals, as well as in mid-dose vector males and some females ...
Biological lipid membranes for on-demand, wireless drug delivery from thin ...
Amounts of the released parathyroid hormone (1–34) were measured by absorbance (optical density) through an enzyme immunoassay kit (Phoenix Pharmaceuticals Inc., Burlingame, CA, USA). Applying a drop (20 μl) of surfactant (Triton X-100, .... Figure 1d ...
What's wrong with the Cardinals and Dodgers so far?
On the Cardinals' side, Piscotty has been about as good as they expected him to be, while Diaz came out of nowhere to bat better than .500 in his first 50 at-bats and has been improving his defense. The Cardinals also have a young hard thrower in the ...
Rogers announces new gigabit internet network, 4K set top box and commitment ...
The service will reportedly cost $150 per month for 1000 megabits download speeds and 50 megabits upload. While 4K is the future of video, the amount of content available in Ultra HD continues to be sparse.
Microsoft Lumia 950 Review: Spearheading Windows 10 Mobile
The Lumia 950 and 950 XL are important products for Microsoft, but not for the reasons you may expect. Microsoft isn't trying to set the mobile market ablaze with these two smartphones.
North State athletes compete in All-Star game
One local athlete will be looking to make an impact in the 11-man game is Corning's Alex Davila. A top playmaker for the Cardinals, Davila accounted for over 50 percent of Corning's total offensive output in 2015. He finished with team-highs in rushing ...
Immunological evidence and regulatory potential for cell-penetrating ...
... Berlin, Germany) containing 10% heat-inactivated fetal bovine serum (FBS; Gibco, Glasgow, UK) were allowed to adhere to microscope coverslips (Glaswarenfabrik, Sondheim/Rh�n, Germany) in 24-well culture plates (Corning, Tewksbury, MA, USA) for 2 ...